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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Superoxide Dismutase 1/SOD1 Antibody Picoband®

SKU : BHA21000290

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Mfr.No.	PB9402, PB9402-10ug, PB9402-Biotin, PB9402-Cy3, PB9402-Dylight488, PB9402-Dylight550, PB9402-Dylight594, PB9402-FITC, PB9402-HRP, PB9402-APC, PB9402-PE, PB9402-iFluor647, PB9402-carrier-free
Alternative Names	Superoxide dismutase (Cu-Zn)
Background	Superoxide dismutases (SOD) are a class of enzymes that catalyze the dismutation of superoxide into oxygen and hydrogen peroxide. As such, they are an important antioxidant defense in nearly all cells exposed to oxygen. One of the exceedingly rare exceptions is Lactobacillus plantarum and related lactobacilli, which use a different mechanism.Cu,Zn-SOD was found widely distributed in the cell cytosol and in the cell nucleus, consistent with it being a soluble cytosolic protein. Mitochondria and secretory compartments did not label for this protein. In human cells, peroxisomes showed a labeling density slightly less than that of cytoplasm.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Superoxide Dismutase 1/SOD1 Antibody Picoband® catalog # PB9402. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Destroys radicals which are normally produced within the cells and which are toxic to biological systems.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of Human SOD1, different from the related mouse and rat sequences by two amino acids.
Isotype	Rabbit IgG
Molecular Weight	16-18 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Superoxide dismutase (Cu-Zn);1.15.1.1;Superoxide dismutase 1;hSod1;SOD1;
Tissue Specificity	High expression in heart, placenta, lung, kidney and prostate.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P00441
Gene Id	6647
Gene Name	SOD1
Sequence	Belongs to the Cu-Zn superoxide dismutase family.
Subcellular Location	Cytoplasm. Nucleus. Predominantly cytoplasmic; the pathogenic variants ALS1 Arg-86 and Ala-94 gradually aggregates and accumulates in mitochondria.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat Immunohistochemistry(Paraffin-embedded Section), 0.5-1 ug/ml, Human, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 2 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Crapo, J. D., Oury, T., Rabouille, C., Slot, J. W., Chang, L.-Y. Copper,zinc superoxide dismutase is primarily a cytosolic protein in human cells. Proc. Nat. Acad. Sci. 89: 10405-10409, 1992.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000290-1	PB9402	100 ug	-	$370		Add to Cart
BHA21000290-2	PB9402-10ug	10 ug	Sample	$99		Add to Cart
BHA21000290-3	PB9402-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000290-4	PB9402-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000290-5	PB9402-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000290-6	PB9402-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000290-7	PB9402-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000290-8	PB9402-FITC	100 ug	FITC	$570		Add to Cart
BHA21000290-9	PB9402-HRP	100 ug	HRP	$570		Add to Cart
BHA21000290-10	PB9402-APC	100 ug	APC	$670		Add to Cart
BHA21000290-11	PB9402-PE	100 ug	PE	$670		Add to Cart
BHA21000290-12	PB9402-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000290-13	PB9402-carrier-free	100 ug	carrier-free	$370		Add to Cart

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