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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Stra8 Antibody Picoband®

SKU : BHA21006865

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Mfr.No.	PA1528, PA1528-10ug, PA1528-Biotin, PA1528-Cy3, PA1528-Dylight488, PA1528-Dylight550, PA1528-Dylight594, PA1528-FITC, PA1528-HRP, PA1528-APC, PA1528-PE, PA1528-iFluor647, PA1528-carrier-free
Alternative Names	stimulated by retinoic acid gene 8 homolog(mouse)
Background	Stra8, stimulated by retinoic acid 8, is expressed in embryonic ovaries just before meiotic initiation, whereas in testis it is expressed after birth. The STRA8 gene contains 9 exons. And this gene is mapped to chromosome 7q31. Retinoic acid (RA) signaling was required for Stra8 expression, and therefore initiation of meiosis, in embryonic mouse ovaries. RA was sufficient to induce Stra8 expression in embryonic testis. Cyp26-mediated RA metabolism was responsible for delaying Stra8 expression in embryonic testis. Since RA signaling regulated Stra8 expression in both embryonic ovaries and adult testis, it was said this portion of the meiotic initiation pathway may be identical in both sexes.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Stra8 Antibody catalog # PA1528. Tested in WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fib
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of rat Stra8, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	37 kDa
Reactivity	Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Protein Stra8 ;Stra8 ;
Tissue Specificity	Present only in vascular endothelium in non- neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	D4ADQ4
Gene Name	STRA8
Sequence	Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Subcellular Location	Cell membrane ; Single-pass type I membrane protein . Melanosome . Colocalizes with SLC16A1 and SLC16A8. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat<br>

Reference	1. Anderson, E. L., Baltus, A. E., Roepers-Gajadien, H. L., Hassold, T. J., de Rooij, D. G., van Pelt, A. M. M., Page, D. C.Stra8 and its inducer, retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice.Proc. Nat. Acad. Sci. 105: 14976-14980, 2008.<br /><br />2. Miyamoto, T., Sengoku, K., Takuma, N., Hasuike, S., Hayashi, H., Yamauchi, T., Yamashita, T., Ishikawa, M.Isolation and expression analysis of the testis-specific gene, STRA8, stimulated by retinoic acid gene 8.J. Assisted Reprod. Genet. 19: 531-535, 2002.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006865-1	PA1528	-	100 ug	$370		Add to Cart
BHA21006865-2	PA1528-10ug	Sample	10 ug	$99		Add to Cart
BHA21006865-3	PA1528-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006865-4	PA1528-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006865-5	PA1528-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006865-6	PA1528-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006865-7	PA1528-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006865-8	PA1528-FITC	FITC	100 ug	$570		Add to Cart
BHA21006865-9	PA1528-HRP	HRP	100 ug	$570		Add to Cart
BHA21006865-10	PA1528-APC	APC	100 ug	$670		Add to Cart
BHA21006865-11	PA1528-PE	PE	100 ug	$670		Add to Cart
BHA21006865-12	PA1528-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006865-13	PA1528-carrier-free	carrier-free	100 ug	$370		Add to Cart

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