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Home / Primary Antibodies / Polyclonal Antibodies

Anti-STAT6 Antibody Picoband®

SKU : BHA21000297

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Mfr.No.	PB9405, PB9405-10ug, PB9405-Biotin, PB9405-Cy3, PB9405-Dylight488, PB9405-Dylight550, PB9405-Dylight594, PB9405-FITC, PB9405-HRP, PB9405-APC, PB9405-PE, PB9405-iFluor647, PB9405-carrier-free
Alternative Names	Signal transducer and activator of transcription 6
Background	STAT6 is a human gene. The protein encoded by this gene is a member of the STAT family of transcription factors. The gene spans 19 kb and contains 23 exons. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X (L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2), expression of cell surface markers, and class switch of immunoglobulins.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-STAT6 Antibody Picoband® catalog # PB9405. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Carries out a dual function: signal transduction and activation of transcription. Involved in IL4/interleukin-4- and IL3/interleukin-3-mediated signaling. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human STAT6, different from the related mouse sequence by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	94 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Signal transducer and activator of transcription 6;IL-4 Stat;STAT6;
Tissue Specificity	Mainly expressed in the developing central nervous system.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P42226
Gene Id	6778
Gene Name	STAT6
Sequence	Belongs to the transcription factor STAT family.
Subcellular Location	Cytoplasm. Nucleus. Translocated into the nucleus in response to phosphorylation.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Rat, Human

Reference	1. Dickensheets, H. L., Venkataraman, C., Schindler, U., Donnelly, R. P.Interferons inhibit activation of STAT6 by interleukin 4 in human monocytes by inducing SOCS-1 gene expression.Proc. Nat. Acad. Sci. 96: 10800-10805, 1999. 2. Duetsch, G., Illig, T., Loesgen, S., Rohde, K., Kloop, N., Herbon, N., Cohlke, H., Altmueller, J., Wjst, M.STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study.Hum. Molec. Genet. 11: 613-621, 2002. 3. Mullings, R. E., Wilson, S. J., Puddicombe, S. M., Lordan, J. L., Bucchieri, F., Djukanovic, R., Howarth, P. H., Harper, S., Holgate, S. T., Davies, D. E.Signal transducer and activator of transcription 6 (STAT-6) expression and function in asthmatic bronchial epithelium.J. Allergy Clin. Immun. 108: 832-838, 2001.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000297-1	PB9405	100 ug	-	$370		Add to Cart
BHA21000297-2	PB9405-10ug	10 ug	Sample	$99		Add to Cart
BHA21000297-3	PB9405-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000297-4	PB9405-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000297-5	PB9405-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000297-6	PB9405-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000297-7	PB9405-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000297-8	PB9405-FITC	100 ug	FITC	$570		Add to Cart
BHA21000297-9	PB9405-HRP	100 ug	HRP	$570		Add to Cart
BHA21000297-10	PB9405-APC	100 ug	APC	$670		Add to Cart
BHA21000297-11	PB9405-PE	100 ug	PE	$670		Add to Cart
BHA21000297-12	PB9405-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000297-13	PB9405-carrier-free	100 ug	carrier-free	$370		Add to Cart

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