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Home / Primary Antibodies / Polyclonal Antibodies

Anti-STAT1 Antibody Picoband®

SKU : BHA21006654

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Mfr.No.	PA1075, PA1075-10ug, PA1075-Biotin, PA1075-Cy3, PA1075-Dylight488, PA1075-Dylight550, PA1075-Dylight594, PA1075-FITC, PA1075-HRP, PA1075-APC, PA1075-PE, PA1075-iFluor647, PA1075-carrier-free
Alternative Names	Signal transducer and activator of transcription 1-alpha/beta
Background	Signal transducer and activator of transcription 1 (STAT1) is a transcription factor which in humans is encoded by the STAT1 gene. The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alteatively spliced transcript variants encoding distinct isoforms have been described.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-STAT1 Antibody catalog # PA1075. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Signal transducer and transcription activator that mediates cellular responses to interferons (IFNs), cytokine KITLG/SCF and other cytokines and other growth factors. Following type I IFN (IFN-alpha and IFN-beta) binding to cell surface receptors, signali
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human STAT1, different from the related mouse sequence by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	91 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Signal transducer and activator of transcription 1-alpha/beta;Transcription factor ISGF-3 components p91/p84;STAT1;
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P42224
Gene Name	STAT1
Sequence	Belongs to the transcription factor STAT family.
Subcellular Location	Cytoplasm . Nucleus . Translocated into the nucleus upon tyrosine phosphorylation and dimerization, in response to IFN-gamma and signaling by activated FGFR1, FGFR2, FGFR3 or FGFR4.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Deberry C, Mou S, Linnekin D (October 1997). "Stat1 associates with c-kit and is activated in response to stem cell factor". Biochem. J. 327 (1): 7380.<br /><br />2. Ouchi T, Lee SW, Ouchi M, Aaronson SA, Horvath CM (May 2000). "Collaboration of signal transducer and activator of transcription 1 (STAT1) and BRCA1 in differential regulation of IFN-gamma target genes".Proc. Natl. Acad. Sci. U.S.A. 97 (10): 520813.<br /><br />3. Zhang JJ, Vinkemeier U, Gu W, Chakravarti D, Horvath CM, Daell JE (Dec 1996). "Two contact regions between Stat1 and CBP/p300 in interferon gamma signaling". Proc. Natl. Acad. Sci. U.S.A. 93 (26): 150926.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006654-1	PA1075	-	100 ug	$370		Add to Cart
BHA21006654-2	PA1075-10ug	Sample	10 ug	$99		Add to Cart
BHA21006654-3	PA1075-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006654-4	PA1075-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006654-5	PA1075-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006654-6	PA1075-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006654-7	PA1075-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006654-8	PA1075-FITC	FITC	100 ug	$570		Add to Cart
BHA21006654-9	PA1075-HRP	HRP	100 ug	$570		Add to Cart
BHA21006654-10	PA1075-APC	APC	100 ug	$670		Add to Cart
BHA21006654-11	PA1075-PE	PE	100 ug	$670		Add to Cart
BHA21006654-12	PA1075-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006654-13	PA1075-carrier-free	carrier-free	100 ug	$370		Add to Cart

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