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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Stanniocalcin 2/STC2 Antibody Picoband®

SKU : BHA21005915

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Mfr.No.	A05017, A05017-10ug, A05017-Biotin, A05017-Cy3, A05017-Dylight488, A05017-Dylight550, A05017-Dylight594, A05017-FITC, A05017-HRP, A05017-APC, A05017-PE, A05017-iFluor647, A05017-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Stanniocalcin-2 is a protein that in humans is encoded by the STC2 gene. This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-Stanniocalcin 2/STC2 Antibody Picoband® catalog # A09658. Tested in WB, IHC, ICC/IF, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human Stanniocalcin 2/STC2 recombinant protein (Position: A51-Q226). Human STC2 shares 90.3% and 89.8% amino acid (aa) sequence identity with mouse and rat STC2, respectively.
Isotype	IgG
Molecular Weight	33 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O76061
Gene Id	8614
Gene Name	STC2
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	ELISA, IF, IHC, ICC, WB, Flow Cytometry
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug /1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Chang, A. C.-M., Reddel, R. R. Identification of a second stanniocalcin cDNA in mouse and human: stanniocalcin 2. Molec. Cell. Endocr. 141: 95-99, 1998.<br /><br />2. DiMattia, G. E., Varghese, R., Wagner, G. F. Molecular cloning and characterization of stanniocalcin-related protein. Molec. Cell. Endocr. 146: 137-140, 1998.<br /><br />3. Ishibashi, K., Miyamoto, K., Taketani, Y., Morita, K., Takeda, E., Sasaki, S., Imai, M. Molecular cloning of a second human stanniocalcin homologue (STC2). Biochem. Biophys. Res. Commun. 250: 252-258, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005915-1	A05017	-	100 ug	$370		Add to Cart
BHA21005915-2	A05017-10ug	Sample	10 ug	$99		Add to Cart
BHA21005915-3	A05017-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005915-4	A05017-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005915-5	A05017-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005915-6	A05017-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005915-7	A05017-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005915-8	A05017-FITC	FITC	100 ug	$570		Add to Cart
BHA21005915-9	A05017-HRP	HRP	100 ug	$570		Add to Cart
BHA21005915-10	A05017-APC	APC	100 ug	$670		Add to Cart
BHA21005915-11	A05017-PE	PE	100 ug	$670		Add to Cart
BHA21005915-12	A05017-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005915-13	A05017-carrier-free	carrier-free	100 ug	$370		Add to Cart

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