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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SRI Antibody Picoband®

SKU : BHA21002069

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Mfr.No.	A00222, A00222-10ug, A00222-Biotin, A00222-Cy3, A00222-Dylight488, A00222-Dylight550, A00222-Dylight594, A00222-FITC, A00222-HRP, A00222-APC, A00222-PE, A00222-iFluor647, A00222-carrier-free
Alternative Names	sorcin
Background	Sorcin is a protein that in humans is encoded by the SRI gene. It is mapped to 7q21.1. This gene encodes a calcium-binding protein with multiple E-F hand domains that relocates from the cytoplasm to the sarcoplasmic reticulum in response to elevated calcium levels. In addition to regulating intracellular calcium homeostasis it also modulates excitation-contraction coupling in the heart. Alteative splicing results in multiple transcript variants encoding distinct proteins. Multiple pseudogenes exist for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SRI Antibody Picoband® catalog # A00222. Tested in Flow Cytometry, IF, IHC, IHC-F, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Calcium-binding protein that modulates excitation-contraction coupling in the heart. Contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Modulates the activity of RYR2 calcium channels.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human SRI, which shares 93.3% amino acid (aa) sequence identity with both mouse and rat SRI.
Isotype	Rabbit IgG
Molecular Weight	22 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Sorcin; 22 kDa protein; CP-22; CP22; V19; SRI
Tissue Specificity	Detected in cardiac myocytes.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	P30626
Gene Id	6717
Gene Name	SRI
Subcellular Location	Cytoplasm. Sarcoplasmic reticulum membrane. Peripheral membrane protein. Cytoplasmic side.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, IHC-F, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunohistochemistry (Frozen Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells<br>

Reference	1. "Entrez Gene: SRI sorcin".<br /><br />2. Meyers, M B; Pickel V M; Sheu S S; Sharma V K; Scotto K W; Fishman G I (Nov 1995). "Association of sorcin with the cardiac ryanodine receptor". J. Biol. Chem. (UNITED STATES) 270 (44): 264118.<br /><br />3. Van der Bliek AM, Baas F, Van der Velde-Koerts T, Biedler JL, Meyers MB, Ozols RF, Hamilton TC, Joenje H, Borst P (Nov 1988). "Genes amplified and overexpressed in human multidrug-resistant cell lines". Cancer Res48 (21): 592732.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002069-1	A00222	-	100 ug	$370		Add to Cart
BHA21002069-2	A00222-10ug	Sample	10 ug	$99		Add to Cart
BHA21002069-3	A00222-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002069-4	A00222-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002069-5	A00222-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002069-6	A00222-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002069-7	A00222-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002069-8	A00222-FITC	FITC	100 ug	$570		Add to Cart
BHA21002069-9	A00222-HRP	HRP	100 ug	$570		Add to Cart
BHA21002069-10	A00222-APC	APC	100 ug	$670		Add to Cart
BHA21002069-11	A00222-PE	PE	100 ug	$670		Add to Cart
BHA21002069-12	A00222-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002069-13	A00222-carrier-free	carrier-free	100 ug	$370		Add to Cart

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