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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Src Antibody Picoband®

SKU : BHA21007517

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Mfr.No.	PB9059, PB9059-10ug, PB9059-Biotin, PB9059-Cy3, PB9059-Dylight488, PB9059-Dylight550, PB9059-Dylight594, PB9059-FITC, PB9059-HRP, PB9059-APC, PB9059-PE, PB9059-iFluor647, PB9059-carrier-free
Alternative Names	Proto-oncogene tyrosine-protein kinase Src
Background	Sarcoma (Scr) is a proto-oncogenic tyrosine kinase originally discovered by J. Michael Bishop and Harold E. Varmus. belongs to a family of non-receptor tyrosine kinases called Src family kinases. The human SRC protooncogene was assigned to chromosome 20. Its gene is mapped to 20q12-q13. The discovery of Src family proteins has been instrumental to the mode understanding of cancer as a disease where normally healthy cellular signalling has gone awry. This proto-oncogene may play a role in the regulation of embryonic development and cell growth.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Src Antibody Picoband® catalog # PB9059. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein- coupled
Host	Rabbit
Immunogen Region	E.coli-derived human Src recombinant protein (Position: G2-D368). Human Src shares 97% and 99% amino acid (aa) sequences identity with mouse and rat Src, respectively.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Proto-oncogene tyrosine-protein kinase Src;2.7.10.2;Proto-oncogene c-Src;pp60c-src;p60-Src;SRC;SRC1;
Tissue Specificity	Expressed ubiquitously. Platelets, neurons and osteoclasts express 5-fold to 200-fold higher levels than most other tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P12931
Gene Id	6714
Gene Name	SRC
Sequence	Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily.
Subcellular Location	Cell membrane. Mitochondrion inner membrane. Nucleus. Cytoplasm, cytoskeleton. Localizes to focal adhesion sites following integrin engagement. Localization to focal adhesion sites requires myristoylation and the SH3 domain.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, By Heat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human

Reference	1. Nobel Prize in Physiology or Medicine for 1989 jointly to J. Michael Bishop and Harold E. Varmus for their discovery of "the cellular origin of retroviral oncogenes". Press Release. 2. Entrez Gene: SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)". 3. Gibbs, C. P., Tanaka, A., Anderson, S. K., Radul, J., Baar, J., Ridgway, A., Kung, H.-J., Fujita, D. J.Isolation and structural mapping of a human c-src gene homologous to the transforming gene (v-src) of Rous sarcoma virus.J. Virol.53: 19-24, 1985.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007517-1	PB9059	-	100 ug	$370		Add to Cart
BHA21007517-2	PB9059-10ug	Sample	10 ug	$99		Add to Cart
BHA21007517-3	PB9059-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007517-4	PB9059-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007517-5	PB9059-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007517-6	PB9059-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007517-7	PB9059-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007517-8	PB9059-FITC	FITC	100 ug	$570		Add to Cart
BHA21007517-9	PB9059-HRP	HRP	100 ug	$570		Add to Cart
BHA21007517-10	PB9059-APC	APC	100 ug	$670		Add to Cart
BHA21007517-11	PB9059-PE	PE	100 ug	$670		Add to Cart
BHA21007517-12	PB9059-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007517-13	PB9059-carrier-free	carrier-free	100 ug	$370		Add to Cart

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