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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SPT5/SUPT5H Antibody Picoband®

SKU : BHA21004265

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Mfr.No.	A03426-2, A03426-2-10ug, A03426-2-Biotin, A03426-2-Cy3, A03426-2-Dylight488, A03426-2-Dylight550, A03426-2-Dylight594, A03426-2-FITC, A03426-2-HRP, A03426-2-APC, A03426-2-PE, A03426-2-iFluor647, A03426-2-carrier-free
Alternative Names	vacuolar protein sorting 4 homolog B
Background	Transcription elongation factor SPT5 is a protein that in humans is encoded by the SUPT5H gene. Enables enzyme binding activity and protein heterodimerization activity. Involved in positive regulation of macroautophagy; regulation of RNA metabolic process; and transcription elongation from RNA polymerase II promoter. Located in nucleoplasm. Part of DSIF complex.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SPT5/SUPT5H Antibody Picoband® catalog # A03426-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Involved in late steps of the endosomal multivesicular bodies (MVB) pathway. Recognizes membrane-associated ESCRT-III assemblies and catalyzes their disassembly, possibly in combination with membrane fission. Redistributes the ESCRT-III components to the
Host	Rabbit
Immunogen Region	E.coli-derived human SPT5/SUPT5H recombinant protein (Position: Q533-A1087).
Isotype	Rabbit IgG
Molecular Weight	150 kDa
Reactivity	Human, Mouse
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Vacuolar protein sorting-associated protein 4B; Cell migration-inducing gene 1 protein; Suppressor of K (+) transport growth defect 1; Protein SKD1; VPS4B; SKD1; VPS42; MIG1
Tissue Specificity	Ubiquitously expressed.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O00267
Gene Id	6829
Gene Name	SUPT5H
Subcellular Location	Late endosome membrane. Peripheral membrane protein. Prevacuolar compartment membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Chiang, P.-W., Fogel, E., Jackson, C. L., Lieuallen, K., Lennon, G., Qu, X., Wang, S.-Q., Kuit, D. M. Isolation, sequencing, and mapping of the human homologue of the yeast transcription factor, SPT5. Genomics 38: 421-424, 1996. <br /><br />2. Chiang, P.-W., Stubbs, L., Zhang, L., Kuit, D. M. Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6. Genomics 47: 426-428, 1998.<br /><br />3. Guo, S., Yamaguchi, Y., Schilbach, S., Wada, T., Lee, J., Goddard, A., French, D., Handa, H., Rosenthal, A. A regulator of transcriptional elongation controls vertebrate neuronal development. Nature 408: 366-369, 2000.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004265-1	A03426-2	-	100 ug	$370		Add to Cart
BHA21004265-2	A03426-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21004265-3	A03426-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004265-4	A03426-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004265-5	A03426-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004265-6	A03426-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004265-7	A03426-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004265-8	A03426-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21004265-9	A03426-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21004265-10	A03426-2-APC	APC	100 ug	$670		Add to Cart
BHA21004265-11	A03426-2-PE	PE	100 ug	$670		Add to Cart
BHA21004265-12	A03426-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004265-13	A03426-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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