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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SPECC1L Antibody Picoband®

SKU : BHA21004901

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Mfr.No.	A09120-1, A09120-1-10ug, A09120-1-Biotin, A09120-1-Cy3, A09120-1-Dylight488, A09120-1-Dylight550, A09120-1-Dylight594, A09120-1-FITC, A09120-1-HRP, A09120-1-APC, A09120-1-PE, A09120-1-iFluor647, A09120-1-carrier-free
Alternative Names	tudor domain containing 3
Background	This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alteatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SPECC1L Antibody Picoband® catalog # A09120-1. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me
Host	Rabbit
Immunogen Region	E.coli-derived human SPECC1L recombinant protein (Position: D177-E959).
Isotype	Rabbit IgG
Molecular Weight	150 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Tudor domain-containing protein 3; TDRD3
Tissue Specificity	Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q69YQ0
Gene Id	23384
Gene Name	SPECC1L
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Allanson, J. E. G syndrome: an unusual family. Am. J. Med. Genet. 31: 637-642, 1988. 2. Bhoj, E. J., Haye, D., Toutain, A., Bonneau, D., Nielsen, I. K., Lund, I. B., Bogaard, P., Leenskjold, S., Karaer, K., Wild, K. T., Grand, K. L., Astiazaran, M. C., and 16 others. Phenotypic spectrum associated with SPEC1L pathogenic variants: new families and critical review of the nosology of Teebi, Opitz GBBB, and Baraitser-Winter syndromes. Europ. J. Med. Genet. 62: 103588, 2019. 3. Bhoj, E. J., Li, D., Harr, M. H., Tian, L., Wang, T., Zhao, Y., Qiu, H., Kim, C., Hoffman, J. D., Hakonarson, H., Zackai, E. H. Expanding the SPECC1L mutation phenotypic spectrum to include Teebi hypertelorism syndrome. Am. J. Med. Genet. 167A: 2497-2502, 2015.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004901-1	A09120-1	-	100 ug	$370		Add to Cart
BHA21004901-2	A09120-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21004901-3	A09120-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004901-4	A09120-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004901-5	A09120-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004901-6	A09120-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004901-7	A09120-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004901-8	A09120-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21004901-9	A09120-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21004901-10	A09120-1-APC	APC	100 ug	$670		Add to Cart
BHA21004901-11	A09120-1-PE	PE	100 ug	$670		Add to Cart
BHA21004901-12	A09120-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004901-13	A09120-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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