JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-SLC12A1 Antibody Picoband®

SKU : BHA21000262

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PB9392, PB9392-10ug, PB9392-Biotin, PB9392-Cy3, PB9392-Dylight488, PB9392-Dylight550, PB9392-Dylight594, PB9392-FITC, PB9392-HRP, PB9392-APC, PB9392-PE, PB9392-iFluor647, PB9392-carrier-free
Alternative Names	Solute carrier family 12 member 1
Background	Solute carrier family 12 (sodium/potassium/chloride transporters), member 1, also called NKCC2 is specifically found in cells of the thick ascending limb of the loop of Henle in nephrons, the basic functional units of the kidney. This gene is mapped to 15q21.1. This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. This gene plays a vital role in the regulation of ionic balance and cell volume.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SLC12A1 Antibody Picoband® catalog # PB9392. Tested in IF, IHC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human SLC12A1, different from the related mouse sequence by two amino acids, and from the related rat sequence by four amino acids.
Isotype	Rabbit IgG
Molecular Weight	150-290 kDa
Reactivity	Human, Monkey, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Solute carrier family 12 member 1;Bumetanide-sensitive sodium- (potassium)-chloride cotransporter 2;Kidney-specific Na-K-Cl symporter;SLC12A1;NKCC2;
Tissue Specificity	Kidney specific.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q13621
Gene Id	6557
Gene Name	SLC12A1
Sequence	Contains 1 PID domain.
Subcellular Location	Membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IF, IHC, WB
Description	Weste blot, 0.25-0.5ug/ml, Monkey, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat, By Heat Immunofluorescence, 5 ug/ml, Mouse, Rat

Reference	1. Nozu, K., Iijima, K., Kawai, K., Nozu, Y., Nishida, A., Takeshima, Y., Fu, X. J., Hashimura, Y., Kaito, H., Nakanishi, K., Yoshikawa, N., Matsuo, M. In vivo and in vitro splicing assay of SLC12A1 in an antenatal salt-losing tubulopathy patient with an intronic mutation. Hum. Genet. 126: 533-538, 2009. 2. Takahashi, N., Cheavvsky, D. R., Gomez, R. A., Igarashi, P., Gitelman, H. J., Smithies, O.Uncompensated polyuria in a mouse model of Bartter's syndrome. Proc. Nat. Acad. Sci. 97: 5434-5439, 2000.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000262-1	PB9392	100 ug	-	$370		Add to Cart
BHA21000262-2	PB9392-10ug	10 ug	Sample	$99		Add to Cart
BHA21000262-3	PB9392-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000262-4	PB9392-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000262-5	PB9392-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000262-6	PB9392-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000262-7	PB9392-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000262-8	PB9392-FITC	100 ug	FITC	$570		Add to Cart
BHA21000262-9	PB9392-HRP	100 ug	HRP	$570		Add to Cart
BHA21000262-10	PB9392-APC	100 ug	APC	$670		Add to Cart
BHA21000262-11	PB9392-PE	100 ug	PE	$670		Add to Cart
BHA21000262-12	PB9392-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000262-13	PB9392-carrier-free	100 ug	carrier-free	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.