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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SLAMF6 Antibody Picoband®

SKU : BHA21005884

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Mfr.No.	A05310-2, A05310-2-10ug, A05310-2-Biotin, A05310-2-Cy3, A05310-2-Dylight488, A05310-2-Dylight550, A05310-2-Dylight594, A05310-2-FITC, A05310-2-HRP, A05310-2-APC, A05310-2-PE, A05310-2-iFluor647, A05310-2-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	SLAM family member 6 is a protein that in humans is encoded by the SLAMF6 gene. The protein encoded by this gene is a type I transmembrane protein, belonging to the CD2 subfamily of the immunoglobulin superfamily. This encoded protein is expressed on Natural killer (NK), T, and B lymphocytes. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases (SHPs). It functions as a coreceptor in the process of NK cell activation. It can also mediate inhibitory signals in NK cells from X-linked lymphoproliferative patients. Alteative splicing results in multiple transcript variants encoding distinct isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-SLAMF6 Antibody Picoband® catalog # A05310-2. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human SLAMF6 recombinant protein (Position: Q22-V332). Human SLAMF6 shares 43.1% amino acid (aa) sequence identity with mouse SLAMF6.
Isotype	IgG
Molecular Weight	60 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q96DU3
Gene Id	114836
Gene Name	SLAMF6
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Bottino, C., Falco, M., Parolini, S., Marcenaro, E., Augugliaro, R., Sivori, S., Landi, E., Biassoni, R., Notarangelo, L. D., Moretta, L., Moretta, A. NTB-A, a novel SH2D1A-associated surface molecule contributing to the inability of natural killer cells to kill Epstein-Barr virus-infected B cells in X-linked lymphoproliferative disease. J. Exp. Med. 194: 235-246, 2001. Note: Erratum: J. Exp. Med. 194: 705 only, 2001.<br /><br />2. Cao, E., Ramagopal, U. A., Fedorov, A., Federov, E., Yan, Q., Lary, J. W., Cole, J. L., Nathenson, S. G., Almo, S. C. NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family. Immunity 25: 559-570, 2006. <br /><br />3. Flaig, R. M., Stark, S., Watzl, C. Cutting edge: NTB-A activates NK cells via homophilic interaction. J. Immun. 172: 6524-6527, 2004.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005884-1	A05310-2	-	100 ug	$370		Add to Cart
BHA21005884-2	A05310-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21005884-3	A05310-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005884-4	A05310-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005884-5	A05310-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005884-6	A05310-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005884-7	A05310-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005884-8	A05310-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21005884-9	A05310-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21005884-10	A05310-2-APC	APC	100 ug	$670		Add to Cart
BHA21005884-11	A05310-2-PE	PE	100 ug	$670		Add to Cart
BHA21005884-12	A05310-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005884-13	A05310-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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