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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Serum Amyloid P/APCS Antibody Picoband®

SKU : BHA21001541

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Mfr.No.	A00162, A00162-10ug, A00162-Biotin, A00162-Cy3, A00162-Dylight488, A00162-Dylight550, A00162-Dylight594, A00162-FITC, A00162-HRP, A00162-APC, A00162-PE, A00162-iFluor647, A00162-carrier-free
Alternative Names	amyloid P component, serum
Background	Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened β-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Serum Amyloid P/APCS Antibody Picoband® catalog # A00162. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
Host	Rabbit
Immunogen Region	E. coli-derived human Serum Amyloid P recombinant protein (Position: H20-L220).
Isotype	Rabbit IgG
Molecular Weight	25-29 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Serum amyloid P-component; SAP; 9.5S alpha-1-glycoprotein; Serum amyloid P-component (1-203); APCS; PTX2
Tissue Specificity	Found in serum and urine.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P02743
Gene Id	325
Gene Name	APCS
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392393.<br /><br />2. "Entrez Gene: APCS amyloid P component, serum".<br /><br />3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 33845.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001541-1	A00162	100 ug	-	$370		Add to Cart
BHA21001541-2	A00162-10ug	10 ug	Sample	$99		Add to Cart
BHA21001541-3	A00162-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001541-4	A00162-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001541-5	A00162-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001541-6	A00162-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001541-7	A00162-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001541-8	A00162-FITC	100 ug	FITC	$570		Add to Cart
BHA21001541-9	A00162-HRP	100 ug	HRP	$570		Add to Cart
BHA21001541-10	A00162-APC	100 ug	APC	$670		Add to Cart
BHA21001541-11	A00162-PE	100 ug	PE	$670		Add to Cart
BHA21001541-12	A00162-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001541-13	A00162-carrier-free	100 ug	carrier-free	$370		Add to Cart

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