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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Serum Amyloid P/APCS Antibody Picoband®

SKU : BHA21007482

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Mfr.No.	PB9020, PB9020-10ug, PB9020-Biotin, PB9020-Cy3, PB9020-Dylight488, PB9020-Dylight550, PB9020-Dylight594, PB9020-FITC, PB9020-HRP, PB9020-APC, PB9020-PE, PB9020-iFluor647, PB9020-carrier-free
Alternative Names	Serum amyloid P-component
Background	Amyloid P component, serum (SAP), also known as PTX2 or APCS, is the identical serum form of amyloid P component (AP), a 25kDa pentameric protein first identified as the pentagonal constituent of in vivo pathological deposits called "amyloid". It belongs to the pentraxins family, characterised by calcium dependent ligand binding and distinctive flattened beta-jellyroll structure similar to that of the legume lectins. This gene is mapped to 1q23.2. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Serum Amyloid P/APCS Antibody Picoband® catalog # PB9020. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans- endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation (By si
Host	Rabbit
Immunogen Region	E.coli-derived mouse Serum Amyloid P recombinant protein (Position: Q21-D224). Mouse Serum Amyloid P shares 70% and 80% amino acid (aa) sequences identity with human and rat Serum Amyloid P, respectively.
Isotype	Rabbit IgG
Molecular Weight	25-29 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Serum amyloid P-component;SAP;Apcs;Ptx2, Sap;
Tissue Specificity	Expressed at low level on a subpopulation of lymphocytes, macrophages, and endothelial cells, but is strongly induced on these cells, and on fibroblasts and epithelial cells.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P12246
Gene Id	20219
Gene Name	APCS
Sequence	Belongs to the pentaxin family.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	ELISA, 0.1-0.5ug/ml, -<br>Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Rat, By Heat<br>Western blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Cathcart ES, Shirahama T, Cohen AS (1967). "Isolation and identification of a plasma component of amyloid". Biochim. Biophy. Acta 147: 392393.<br /><br />2. "Entrez Gene: APCS amyloid P component, serum".<br /><br />3. Emsley J, White HE, O'Hara BP, Oliva G, Srinivasan N, Tickle IJ, Blundell TL, Pepys MB, Wood SP (1994). "Structure of pentameric human serum amyloid P component". Nature 367 (6461): 33845.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007482-1	PB9020	-	100 ug	$370		Add to Cart
BHA21007482-2	PB9020-10ug	Sample	10 ug	$99		Add to Cart
BHA21007482-3	PB9020-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007482-4	PB9020-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007482-5	PB9020-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007482-6	PB9020-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007482-7	PB9020-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007482-8	PB9020-FITC	FITC	100 ug	$570		Add to Cart
BHA21007482-9	PB9020-HRP	HRP	100 ug	$570		Add to Cart
BHA21007482-10	PB9020-APC	APC	100 ug	$670		Add to Cart
BHA21007482-11	PB9020-PE	PE	100 ug	$670		Add to Cart
BHA21007482-12	PB9020-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007482-13	PB9020-carrier-free	carrier-free	100 ug	$370		Add to Cart

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