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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SENP1 Antibody Picoband®

SKU : BHA21002455

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Mfr.No.	A02156-3, A02156-3-10ug, A02156-3-Biotin, A02156-3-Cy3, A02156-3-Dylight488, A02156-3-Dylight550, A02156-3-Dylight594, A02156-3-FITC, A02156-3-HRP, A02156-3-APC, A02156-3-PE, A02156-3-iFluor647, A02156-3-carrier-free
Alternative Names	SUMO specific peptidase 1
Background	Sentrin-specific protease 1 is a protein that in human is encoded by the SENP1 gene. This gene is mapped to 12q13.11. This gene encodes a cysteine protease that specifically targets members of the small ubiquitin-like modifier (SUMO) protein family. This protease regulates SUMO pathways by deconjugating sumoylated proteins. This protease also functions to process the precursor SUMO proteins into their mature form. Alteate splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SENP1 Antibody Picoband® catalog # A02156-3. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Protease that catalyzes two essential functions in the SUMO pathway. The first is the hydrolysis of an alpha-linked peptide bond at the C-terminal end of the small ubiquitin-like modifier (SUMO) propeptides, SUMO1, SUMO2 and SUMO3 leading to the mature fo
Host	Rabbit
Immunogen Region	E.coli-derived human SENP1 recombinant protein (Position: N19-P619).
Isotype	Rabbit IgG
Molecular Weight	73 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Sentrin-specific protease 1; Sentrin/SUMO-specific protease SENP1; SENP1
Tissue Specificity	Highly expressed in testis. Expressed at lower levels in thymus, pancreas, spleen, liver, ovary and small intestine.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9P0U3
Gene Id	29843
Gene Name	SENP1
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Veltman, I. M., Vreede, L. A., Cheng, J., Looijenga, L. H. J., Janssen, B., Schoenmakers, E. F. P. M., Yeh, E. T. H., Geurts van Kessel, A. Fusion of the SUMO/sentrin-specific protease 1 gene SENP1 and the embryonic polarity-related mesoderm development gene MESDC2 in a patient with an infantile teratoma and a constitutional t(12;15)(q13;q25). Hum. Molec. Genet. 14: 1955-1963, 2005.<br /><br />2. Yamaguchi, T., Sharma, P., Athanasiou, M., Kumar, A., Yamada, S., Kuehn, M. R. Mutation of SENP1/SuPr-2 reveals an essential role for desumoylation in mouse development. Molec. Cell. Biol. 25: 5171-5182, 2005.<br /><br />3. Yu, L., Ji, W., Zhang, H., Renda, M. J., He, Y., Lin, S., Cheng, E., Chen, H., Krause, D. S., Min, W. SENP1-mediated GATA1 deSUMOylation is critical for definitive erythropoiesis. J. Exp. Med. 207: 1183-1195, 2010.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002455-1	A02156-3	-	100 ug	$370		Add to Cart
BHA21002455-2	A02156-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21002455-3	A02156-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002455-4	A02156-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002455-5	A02156-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002455-6	A02156-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002455-7	A02156-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002455-8	A02156-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21002455-9	A02156-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21002455-10	A02156-3-APC	APC	100 ug	$670		Add to Cart
BHA21002455-11	A02156-3-PE	PE	100 ug	$670		Add to Cart
BHA21002455-12	A02156-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002455-13	A02156-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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