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Home / Primary Antibodies / Polyclonal Antibodies

Anti-SCIN Antibody Picoband®

SKU : BHA21004693

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Mfr.No.	A07463, A07463-10ug, A07463-Biotin, A07463-Cy3, A07463-Dylight488, A07463-Dylight550, A07463-Dylight594, A07463-FITC, A07463-HRP, A07463-APC, A07463-PE, A07463-iFluor647, A07463-carrier-free
Alternative Names	BAG family molecular chaperone regulator 5
Background	Scinderin (also known as adseverin) is a protein that in humans is encoded by the SCIN gene. Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network undeeath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity).
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-SCIN Antibody Picoband® catalog # A07463. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. .
Host	Rabbit
Immunogen Region	E.coli-derived human SCIN recombinant protein (Position: S35-Y617).
Isotype	Rabbit IgG
Molecular Weight	80 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	BAG family molecular chaperone regulator 5;BAG-5;Bcl-2-associated athanogene 5;BAG5;KIAA0873;
Tissue Specificity	Expressed in all tissues examined with lower levels in brain and testis.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9Y6U3
Gene Id	85477
Gene Name	SCIN
Subcellular Location	Perinuclear region.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat ELISA, 0.1-0.5 ug/ml, -

Reference	1. Ehre, C., Rossi, A. H., Abdullah, L. H., De Pestel, K., Hill, S., Olsen, J. C., Davis, C. W. Barrier role of actin filaments in regulated mucin secretion from airway goblet cells. Am. J. Physiol. Cell Physiol. 288: C46-C56, 2005. 2. Gross, M. B. Personal Communication. Baltimore, Md. 5/20/2010. 3. Nagase, T., Kikuno, R., Ohara, O. Prediction of the coding sequences of unidentified human genes. XXI. The complete sequences of 60 new cDNA clones from brain which code for large proteins. DNA Res. 8: 179-187, 2001.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004693-1	A07463	-	100 ug	$370		Add to Cart
BHA21004693-2	A07463-10ug	Sample	10 ug	$99		Add to Cart
BHA21004693-3	A07463-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004693-4	A07463-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004693-5	A07463-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004693-6	A07463-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004693-7	A07463-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004693-8	A07463-FITC	FITC	100 ug	$570		Add to Cart
BHA21004693-9	A07463-HRP	HRP	100 ug	$570		Add to Cart
BHA21004693-10	A07463-APC	APC	100 ug	$670		Add to Cart
BHA21004693-11	A07463-PE	PE	100 ug	$670		Add to Cart
BHA21004693-12	A07463-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004693-13	A07463-carrier-free	carrier-free	100 ug	$370		Add to Cart

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