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Home / Primary Antibodies / Polyclonal Antibodies

Anti-S100A9 Antibody Picoband®

SKU : BHA21000576

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Mfr.No.	PB9677, PB9677-10ug, PB9677-Biotin, PB9677-Cy3, PB9677-Dylight488, PB9677-Dylight550, PB9677-Dylight594, PB9677-FITC, PB9677-HRP, PB9677-APC, PB9677-PE, PB9677-iFluor647, PB9677-carrier-free
Alternative Names	Protein S100-A9
Background	S100 calcium-binding protein A9 (S100A9), also known as migration inhibitory factor-related protein 14 (MRP14) or calgranulin B, is a protein that in humans is encoded by the S100A9 gene. S100-A9 is a member of the S100 family of proteins containing 2 EF hand calcium-binding motifs. And S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with recombinant mouse S100A9 is observed.
Description	Boster Bio Anti-S100A9 Antibody Picoband® catalog # PB9677. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	S100A9 is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting p
Host	Rabbit
Immunogen Region	E. coli-derived human S100A9 recombinant protein (Position: T2-P114). Human S100A9 shares 59.8% and 64.5% amino acid (aa) sequence identity with mouse and rat S100A9, respectively.
Isotype	Rabbit IgG
Molecular Weight	13 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with recombinant mouse S100A9 is observed.
Synonyms	Protein S100-A9;Calgranulin-B;Calprotectin L1H subunit;Leukocyte L1 complex heavy chain;Migration inhibitory factor-related protein 14;MRP-14;p14;S100 calcium-binding protein A9;S100A9;CAGB, CFAG, MRP14;
Tissue Specificity	Calprotectin (S100A8/9) is predominantly expressed in myeloid cells. Except for inflammatory conditions, the expression is restricted to a specific stage of myeloid differentiation since both proteins are expressed in circulating neutrophils and monocytes but are absent in normal tissue macrophages and lymphocytes. Under chronic inflammatory conditions, such as psoriasis and malignant disorders, also expressed in the epidermis. Found in high concentrations at local sites of inflammation or in the serum of patients with inflammatory diseases such as rheumatoid, cystic fibrosis, inflammatory bowel disease, Crohn's disease, giant cell arteritis, cystic fibrosis, Sjogren's syndrome, systemic lupus erythematosus, and progressive systemic sclerosis. Involved in the formation and deposition of amyloids in the aging prostate known as corpora amylacea inclusions. Strongly up-regulated in many tumors, including gastric, esophageal, colon, pancreatic, bladder, ovarian, thyroid, breast and skin cancers. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P06702
Gene Id	6280
Gene Name	S100A9
Subcellular Location	Secreted. Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane; Peripheral membrane protein. Predominantly localized in the cytoplasm. Upon elevation of the intracellular calcium level, translocated from the cytoplasm to the cytoskeleton and the cell membrane. Upon neutrophil activation or endothelial adhesion of monocytes, is secreted via a microtubule-mediated, alteative pathway.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat ELISA, 0.1-0.5ug/ml, - Immunocytochemistry/Immunofluorescence, 5ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human Weste blot, 0.1-0.5ug/ml, Human

Reference	1. "Entrez Gene: S100A9 S100 calcium binding protein A9". 2. Cheng P, Corzo CA, Luetteke N, Yu B, Nagaraj S, Bui MM, Ortiz M, Nacken W, Sorg C, Vogl T, Roth J, Gabrilovich DI (September 2008). "Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein". J. Exp. Med. 205 (10): 223549.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000576-1	PB9677	100 ug	-	$370		Add to Cart
BHA21000576-2	PB9677-10ug	10 ug	Sample	$99		Add to Cart
BHA21000576-3	PB9677-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000576-4	PB9677-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000576-5	PB9677-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000576-6	PB9677-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000576-7	PB9677-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000576-8	PB9677-FITC	100 ug	FITC	$570		Add to Cart
BHA21000576-9	PB9677-HRP	100 ug	HRP	$570		Add to Cart
BHA21000576-10	PB9677-APC	100 ug	APC	$670		Add to Cart
BHA21000576-11	PB9677-PE	100 ug	PE	$670		Add to Cart
BHA21000576-12	PB9677-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000576-13	PB9677-carrier-free	100 ug	carrier-free	$370		Add to Cart

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