JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-RUNX3 Antibody Picoband®

SKU : BHA21000327

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PB9432, PB9432-10ug, PB9432-Biotin, PB9432-Cy3, PB9432-Dylight488, PB9432-Dylight550, PB9432-Dylight594, PB9432-FITC, PB9432-HRP, PB9432-APC, PB9432-PE, PB9432-iFluor647, PB9432-carrier-free
Alternative Names	Runt-related transcription factor 3
Background	Runt-related transcription factor 3, also called AML2 is a protein that in humans is encoded by the RUNX3 gene. The RUNX3 gene encodes a Runt-related transcription factor, which is part of the RUNX gene family. By fluorescence in situ hybridization, RUNX3 was assigned to human chromosome 1p36.11. RUNX3 binds to the core site of murine Leukemia virus, the core sequences in the enhancer of the polyomavirus, and also to the enhancers of the T-cell receptor genes. It may be involved in the control of cellular proliferation and/or differentiation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-RUNX3 Antibody Picoband® catalog # PB9432. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters.
Host	Rabbit
Immunogen Region	E.coli-derived human RUNX3 recombinant protein (Position: M128-Y270). Human RUNX3 shares 93% amino acid (aa) sequence identity with mouse RUNX3.
Isotype	Rabbit IgG
Molecular Weight	43-48 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Runt-related transcription factor 3;Acute myeloid leukemia 2 protein;Core-binding factor subunit alpha-3;CBF-alpha-3;Oncogene AML-2;Polyomavirus enhancer-binding protein 2 alpha C subunit;PEA2-alpha C;PEBP2-alpha C;SL3-3 enhancer factor 1 alpha C subunit;SL3/AKV core-binding factor alpha C subunit;RUNX3;AML2, CBFA3, PEBP2A3;
Tissue Specificity	Isoform B is predominantly identified in skin and epithelial tissues from the intestinal tract. Its expression is elevated in colorectal tumors at various stages of neoplastic progression, as compared to their respective adjacent tissues.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q13761
Gene Id	864
Gene Name	RUNX3
Sequence	Belongs to the small GTPase superfamily. Rho family.
Subcellular Location	Nucleus . Cytoplasm . The tyrosine phosphorylated form localizes to the cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat, By Heat Immunocytochemistry/Immunofluorescence, 2ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. Brenner, O., Levanon, D., Negreanu, V., Golubkov, O., Fainaru, O., Woolf, E., Groner, Y. Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc. Nat. Acad. Sci. 101: 16016-16021, 2004. 2. Fainaru, O., Shseyov, D., Hantisteanu, S., Groner, Y. Accelerated chemokine receptor 7-mediated dendritic cell migration in Runx3 knockout mice and the spontaneous development of asthma-like disease. Proc. Nat. Acad. Sci. 102: 10598-10603, 2005. 3. Ito, K., Liu, Q., Salto-Tellez, M., Yano, T., Tada, K., Ida, H., Huang, C., Shah, N., Inoue, M., Rajnakova, A., Hiong, K. C., Peh, B. K., Han, H. C., Ito, T., Teh, M., Yeoh, K. G., Ito, Y. RUNX3, a novel tumor suppressor, is frequently inactivated in gastric cancer by protein mislocalization. Cancer Res. 65: 7743-7750, 2005. 4. Li, Q.-L., Ito, K., Sakakura, C., Fukamachi, H., Inoue, K., Chi, X.-Z., Lee, K.-Y., Nomura, S., Lee, C.-W., Han, S.-B., Kim, H.-M., Kim, W.-J., and 15 others. Causal relationship between the loss of RUNX3 expression and gastric cancer. Cell 109: 113-124, 2002.

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000327-1	PB9432	100 ug	-	$370		Add to Cart
BHA21000327-2	PB9432-10ug	10 ug	Sample	$99		Add to Cart
BHA21000327-3	PB9432-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000327-4	PB9432-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000327-5	PB9432-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000327-6	PB9432-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000327-7	PB9432-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000327-8	PB9432-FITC	100 ug	FITC	$570		Add to Cart
BHA21000327-9	PB9432-HRP	100 ug	HRP	$570		Add to Cart
BHA21000327-10	PB9432-APC	100 ug	APC	$670		Add to Cart
BHA21000327-11	PB9432-PE	100 ug	PE	$670		Add to Cart
BHA21000327-12	PB9432-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000327-13	PB9432-carrier-free	100 ug	carrier-free	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.