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Home / Primary Antibodies / Polyclonal Antibodies

Anti-RSK3/RPS6KA2 Antibody Picoband®

SKU : BHA21001950

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Mfr.No.	A06142-1, A06142-1-10ug, A06142-1-Biotin, A06142-1-Cy3, A06142-1-Dylight488, A06142-1-Dylight550, A06142-1-Dylight594, A06142-1-FITC, A06142-1-HRP, A06142-1-APC, A06142-1-PE, A06142-1-iFluor647, A06142-1-carrier-free
Alternative Names	ribosomal protein S6 kinase A2
Background	Ribosomal protein S6 kinase alpha-2 is an enzyme that in humans is encoded by the RPS6KA2 gene. It is mapped to 6q27. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains two non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alteative splice variants, encoding different isoforms, have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RSK3/RPS6KA2 Antibody Picoband® catalog # A06142-1. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and diff
Host	Rabbit
Immunogen Region	E. coli-derived human RSK3 recombinant protein (Position: H658-L733).
Isotype	Rabbit IgG
Molecular Weight	90-100 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Ribosomal protein S6 kinase alpha-2; S6K-alpha-2; 90 kDa ribosomal protein S6 kinase 2; p90-RSK 2; p90RSK2; MAP kinase-activated protein kinase 1c; MAPK-activated protein kinase 1c; MAPKAP kinase 1c; MAPKAPK-1c; Ribosomal S6 kinase 3; RSK-3; pp90RSK3; RPS6KA2; MAPKAPK1C; RSK3
Tissue Specificity	Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q15349
Gene Id	6196
Gene Name	RPS6KA2
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> Immunocytochemistry/Immunofluorescence, 2ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Zeniou, M., Ding, T., Trivier, E., Hanauer, A. Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and leaing. Hum. Molec. Genet. 11: 2929-2940, 2002.<br /><br />2. Zhao, Y., Bjorbaek, C., Weremowicz, S., Morton, C. C., Moller, D. E. RSK3 encodes a novel pp90rsk isoform with a unique N-terminal sequence: growth factor-stimulated kinase function and nuclear translocation. Molec. Cell. Biol. 15: 4353-4363, 1995.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001950-1	A06142-1	100 ug	-	$370		Add to Cart
BHA21001950-2	A06142-1-10ug	10 ug	Sample	$99		Add to Cart
BHA21001950-3	A06142-1-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001950-4	A06142-1-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001950-5	A06142-1-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001950-6	A06142-1-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001950-7	A06142-1-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001950-8	A06142-1-FITC	100 ug	FITC	$570		Add to Cart
BHA21001950-9	A06142-1-HRP	100 ug	HRP	$570		Add to Cart
BHA21001950-10	A06142-1-APC	100 ug	APC	$670		Add to Cart
BHA21001950-11	A06142-1-PE	100 ug	PE	$670		Add to Cart
BHA21001950-12	A06142-1-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001950-13	A06142-1-carrier-free	100 ug	carrier-free	$370		Add to Cart

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