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Home / Primary Antibodies / Polyclonal Antibodies

Anti-RPGR Antibody Picoband®

SKU : BHA21001675

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Mfr.No.	A01522, A01522-10ug, A01522-Biotin, A01522-Cy3, A01522-Dylight488, A01522-Dylight550, A01522-Dylight594, A01522-FITC, A01522-HRP, A01522-APC, A01522-PE, A01522-iFluor647, A01522-carrier-free
Alternative Names	retinitis pigmentosa GTPase regulator
Background	X-linked retinitis pigmentosa GTPase regulator is a GTPase-binding protein that in humans is encoded by the RPGR gene. This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alteatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RPGR Antibody Picoband® catalog # A01522. Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in s
Host	Rabbit
Immunogen Region	E. coli-derived human RPGR recombinant protein (Position: A13-F338).
Isotype	Rabbit IgG
Molecular Weight	113 kDa
Reactivity	Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	X-linked retinitis pigmentosa GTPase regulator; RPGR; RP3; XLRP3
Tissue Specificity	Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q92834
Gene Id	6103
Gene Name	RPGR
Subcellular Location	Cytoplasm, cytoskeleton, flagellum axoneme.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, ELISA
Description	Weste blot, 0.1-0.5ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. "Entrez Gene: RPGR retinitis pigmentosa GTPase regulator".<br /><br />2. Murga-Zamalloa CA, Atkins SJ, Peranen J, Swaroop A, Khanna H (Sep 2010). "Interaction of retinitis pigmentosa GTPase regulator (RPGR) with RAB8A GTPase: implications for cilia dysfunction and photoreceptor degeneration". Human Molecular Genetics. 19 (18): 35918.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21001675-1	A01522	100 ug	-	$370		Add to Cart
BHA21001675-2	A01522-10ug	10 ug	Sample	$99		Add to Cart
BHA21001675-3	A01522-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21001675-4	A01522-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21001675-5	A01522-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21001675-6	A01522-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21001675-7	A01522-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21001675-8	A01522-FITC	100 ug	FITC	$570		Add to Cart
BHA21001675-9	A01522-HRP	100 ug	HRP	$570		Add to Cart
BHA21001675-10	A01522-APC	100 ug	APC	$670		Add to Cart
BHA21001675-11	A01522-PE	100 ug	PE	$670		Add to Cart
BHA21001675-12	A01522-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21001675-13	A01522-carrier-free	100 ug	carrier-free	$370		Add to Cart

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