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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband®

SKU : BHA21000786

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Mfr.No.	PB9885, PB9885-10ug, PB9885-Biotin, PB9885-Cy3, PB9885-Dylight488, PB9885-Dylight550, PB9885-Dylight594, PB9885-FITC, PB9885-HRP, PB9885-APC, PB9885-PE, PB9885-iFluor647, PB9885-carrier-free
Alternative Names	Ribonuclease inhibitor
Background	Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the tuover of RNA in eukaryotic cells, RNH may be essential for control of mRNA tuover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® catalog # PB9885. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis. .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human, Monkey, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Ribonuclease inhibitor;Placental ribonuclease inhibitor;Placental RNase inhibitor;Ribonuclease/angiogenin inhibitor 1;RAI;RNH1;PRI, RNH;
Tissue Specificity	Widely expressed; high expression found in skeletal muscle. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P13489
Gene Id	6050
Gene Name	RNH1
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, By Heat Immunohistochemistry (Frozen Section), 0.5-1ug/ml Immunocytochemistry, 0.5-1ug/ml Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells

Reference	1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 71721. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 1758.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000786-1	PB9885	100 ug	-	$370		Add to Cart
BHA21000786-2	PB9885-10ug	10 ug	Sample	$99		Add to Cart
BHA21000786-3	PB9885-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000786-4	PB9885-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000786-5	PB9885-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000786-6	PB9885-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000786-7	PB9885-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000786-8	PB9885-FITC	100 ug	FITC	$570		Add to Cart
BHA21000786-9	PB9885-HRP	100 ug	HRP	$570		Add to Cart
BHA21000786-10	PB9885-APC	100 ug	APC	$670		Add to Cart
BHA21000786-11	PB9885-PE	100 ug	PE	$670		Add to Cart
BHA21000786-12	PB9885-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000786-13	PB9885-carrier-free	100 ug	carrier-free	$370		Add to Cart

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