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Home / Primary Antibodies / Polyclonal Antibodies

Anti-RGS9 Antibody Picoband®

SKU : BHA21007418

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Mfr.No.	PA2241, PA2241-10ug, PA2241-Biotin, PA2241-Cy3, PA2241-Dylight488, PA2241-Dylight550, PA2241-Dylight594, PA2241-FITC, PA2241-HRP, PA2241-APC, PA2241-PE, PA2241-iFluor647, PA2241-carrier-free
Alternative Names	Regulator of G-protein signaling 9
Background	Regulator of G-protein signaling 9, also known as RGS9 is a human gene, which codes for a protein involved in regulation of signal transduction inside cells. This gene is mapped to 17q24.1. This gene encodes a member of the RGS family of GTPase activating proteins that function in various signaling pathways by accelerating the deactivation of G proteins. This protein is anchored to photoreceptor membranes in retinal cells and deactivates G proteins in the rod and cone phototransduction cascades. Mutations in this gene result in bradyopsia. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-RGS9 Antibody catalog # PA2241. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G (t)-alpha. Involved in phototransduction; key element in the recovery phase of visual transducti
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human RGS9, different from the related mouse and rat sequences by three amino acids.
Isotype	Rabbit IgG
Molecular Weight	56 kDa, 77 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Regulator of G-protein signaling 9;RGS9;RGS9;
Tissue Specificity	Highly expressed in the caudate and putamen, lower levels found in the hypothalamus and nucleus accumbens and very low levels in cerebellum. Not expressed in globus pallidus or cingulate cortex. Isoform 2 is expressed predominantly in pineal gland and retina. Isoform 3 is expressed in retina (abundant in photoreceptors).
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	O75916
Gene Name	RGS9
Sequence	Contains 1 DEP domain.
Subcellular Location	Isoform 3: Membrane; Peripheral membrane protein. Isoform 3 is targeted to the membrane via its interaction with RGS9BP. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Cabrera-Vera, T. M., Heandez, S., Earls, L. R., Medkova, M., Sundgren-Andersson, A. K., Surmeier, D. J., Hamm, H. E. RGS9-2 modulates D2 dopamine receptor-mediated Ca(2+) channel inhibition in rat striatal cholinergic inteeurons. Proc. Nat. Acad. Sci. 101: 16339-16344, 2004.<br /><br />2. Hu, G., Zhang, Z., Wensel, T. G. Activation of RGS9-1GTPase acceleration by its membrane anchor, R9AP. J. Biol. Chem. 278: 14550-14554, 2003.<br /><br />3. Sierra, D. A., Gilbert, D. J., Householder, D., Grishin, N. V., Yu, K., Ukidwe, P., Barker, S. A., He, W., Wensel, T. G., Otero, G., Brown, G., Copeland, N. G., Jenkins, N. A., Wilkie, T. M. Evolution of the regulators of G-protein signaling multigene family in mouse and human. Genomics 79: 177-185, 2002.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007418-1	PA2241	-	100 ug	$370		Add to Cart
BHA21007418-2	PA2241-10ug	Sample	10 ug	$99		Add to Cart
BHA21007418-3	PA2241-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007418-4	PA2241-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007418-5	PA2241-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007418-6	PA2241-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007418-7	PA2241-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007418-8	PA2241-FITC	FITC	100 ug	$570		Add to Cart
BHA21007418-9	PA2241-HRP	HRP	100 ug	$570		Add to Cart
BHA21007418-10	PA2241-APC	APC	100 ug	$670		Add to Cart
BHA21007418-11	PA2241-PE	PE	100 ug	$670		Add to Cart
BHA21007418-12	PA2241-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007418-13	PA2241-carrier-free	carrier-free	100 ug	$370		Add to Cart

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