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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody Picoband®

SKU : BHA21006972

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Mfr.No.	PA1671, PA1671-10ug, PA1671-Biotin, PA1671-Cy3, PA1671-Dylight488, PA1671-Dylight550, PA1671-Dylight594, PA1671-FITC, PA1671-HRP, PA1671-APC, PA1671-PE, PA1671-iFluor647, PA1671-carrier-free
Alternative Names	Retinal dehydrogenase 1
Background	ALDH1A1 (Aldehyde dehydrogenase 1 family, member A1), also called ALDH1, RALDH1 or ALDH, LIVER CYTOSOLIC, is an enzyme that in humans is encoded by the ALDH1A1 gene. And this protein belongs to the aldehyde dehydrogenases family of proteins. The ALDH1A1 gene is mapped on 9q21.13. ALDH1A1 also belongs to the group of coeal crystallins that help maintain the transparency of the coea.ALDH1A1 is associated with a low Km for NAD, a high Km for acetaldehyde, and is strongly inactivated by disulfiram. The ALDH1 gene is about 53 kb long and is divided into 13 exons. Retinaldehyde is generated by ADH1 from retinol, and its concentration is determined in large part by its subsequent catabolism by RALDH1 to retinoic acid.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Retinal dehydrogenase 1 ALDH1A1 Antibody catalog # PA1671. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Binds free retinal and cellular retinol-binding protein- bound retinal. Can convert/oxidize retinaldehyde to retinoic acid (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human ALDH1A1, different from the related rat and mouse sequences by one amino acid.
Isotype	Rabbit IgG
Molecular Weight	65 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Retinal dehydrogenase 1;RALDH 1;RalDH1;1.2.1.36;ALDH-E1;ALHDII;Aldehyde dehydrogenase family 1 member A1;Aldehyde dehydrogenase, cytosolic;ALDH1A1;ALDC, ALDH1, PUMB1;
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	P00352
Gene Name	ALDH1A1
Sequence	Belongs to the aldehyde dehydrogenase family.
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5 ug/ml, Human, Mouse, Rat<br>, Immunohistochemistry (Paraffin-embedded Section), 2-5 ug/ml, Human, By Heat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br>

Reference	1. Eckey, R., Agarwal, D. P., Saha, N., Goedde, H. W. Detection and partial characterization of a variant form of cytosolic aldehyde dehydrogenase isozyme. Hum. Genet. 72: 95-97, 1986.<br /><br />2. Hempel, J., von Bahr-Lindstrom, H., Jovall, H. Aldehyde dehydrogenase from human liver: primary structure of the cytoplasmic isoenzyme. Europ. J. Biochem. 141: 21-35, 1984.<br /><br />3. Pereira F, Rosenmann E, Nylen E, Kaufman M, Pinsky L, Wrogemann K (March 1991). "The 56 kDa androgen binding protein is an aldehyde dehydrogenase". Biochem. Biophys. Res. Commun. 175 (3): 8318.<br /><br /><br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006972-1	PA1671	-	100 ug	$370		Add to Cart
BHA21006972-2	PA1671-10ug	Sample	10 ug	$99		Add to Cart
BHA21006972-3	PA1671-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006972-4	PA1671-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006972-5	PA1671-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006972-6	PA1671-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006972-7	PA1671-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006972-8	PA1671-FITC	FITC	100 ug	$570		Add to Cart
BHA21006972-9	PA1671-HRP	HRP	100 ug	$570		Add to Cart
BHA21006972-10	PA1671-APC	APC	100 ug	$670		Add to Cart
BHA21006972-11	PA1671-PE	PE	100 ug	$670		Add to Cart
BHA21006972-12	PA1671-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006972-13	PA1671-carrier-free	carrier-free	100 ug	$370		Add to Cart

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