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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Resistin/RETN Antibody Picoband®

SKU : BHA21006819

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Mfr.No.	PA1473, PA1473-10ug, PA1473-Biotin, PA1473-Cy3, PA1473-Dylight488, PA1473-Dylight550, PA1473-Dylight594, PA1473-FITC, PA1473-HRP, PA1473-APC, PA1473-PE, PA1473-iFluor647, PA1473-carrier-free
Alternative Names	Resistin
Background	Resistin, also known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) is a cysteine-rich protein that in humans is encoded by the RETN gene. The resistin gene comprises 4 exons, the first of which is untranslated, and spans approximately 1,750 bp. The human resistin gene is localized to a cloned fragment of human chromosome 19. In primates, pigs and dogs, resistin is secreted by immune and epithelial cells while in rodents, it is secreted by adipose tissue. Resistin is a cytokine whose physiologic role has been the subject of much controversy regarding its involvement with obesity and type II diabetes mellitus.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Resistin/RETN Antibody catalog # PA1473. Tested in IHC, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of mouse Resistin.
Isotype	Rabbit IgG
Molecular Weight	38 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Resistin;Adipose tissue-specific secretory factor;ADSF;Adipose-specific cysteine-rich secreted protein A12-alpha;Cysteine-rich secreted protein FIZZ3;Retn;Fizz3;
Tissue Specificity	Expressed in white but not brown adipose tissue in a variety of organs.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q99P87
Gene Name	RETN
Sequence	Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Mouse<br>

Reference	1. Holcomb, I. N., Kabakoff, R. C., Chan, B., Baker, T. W., Guey, A., Henzel, W., Nelson, C., Lowman, H. B., Wright, B. D., Skelton, N. J., Frantz, G. D., Tumas, D. B., Peale, F. V., Jr., Shelton, D. L., Hebert, C. C.FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family.EMBO J. 19: 4046-4055, 2000.<br /><br />2. Steppan, C. M., Bailey, S. T., Bhat, S., Brown, E. J., Banerjee, R. R., Wright, C. M., Patel, H. R., Ahima, R. S., Lazar, M. A.The hormone resistin links obesity to diabetes.Nature 409: 307-312, 2001.<br /><br />3. Wang, H., Chu, W. S., Hemphill, C., Elbein, S. C.Human resistin gene: molecular scanning and evaluation of association with insulin sensitivity and type 2 diabetes in Caucasians.J. Clin. Endocr. Metab. 87: 2520-2524, 2002.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006819-1	PA1473	-	100 ug	$370		Add to Cart
BHA21006819-2	PA1473-10ug	Sample	10 ug	$99		Add to Cart
BHA21006819-3	PA1473-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006819-4	PA1473-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006819-5	PA1473-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006819-6	PA1473-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006819-7	PA1473-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006819-8	PA1473-FITC	FITC	100 ug	$570		Add to Cart
BHA21006819-9	PA1473-HRP	HRP	100 ug	$570		Add to Cart
BHA21006819-10	PA1473-APC	APC	100 ug	$670		Add to Cart
BHA21006819-11	PA1473-PE	PE	100 ug	$670		Add to Cart
BHA21006819-12	PA1473-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006819-13	PA1473-carrier-free	carrier-free	100 ug	$370		Add to Cart

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