JavaScript is currently not supported/disabled by this browser. Please enable JavaScript for full functionality.

Call Us 1 - 866 - 986 - 9598
orders@biohippo.com

Sign Up

Login
- My Order
- Return Requests
- Track my Order

Home / Primary Antibodies / Polyclonal Antibodies

Anti-Rel B/RELB Antibody Picoband®

SKU : BHA21007071

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Request More Infos

Boster

view supplier details

Order Now

Credit card payments now incur a 3% fee.

Contact us to order

Tel

+1 866.986.9598

Email

orders@biohippo.com

Get a Quote

Ask Merchant

Request More Infos

Sample Request

Mfr.No.	PA1803, PA1803-10ug, PA1803-Biotin, PA1803-Cy3, PA1803-Dylight488, PA1803-Dylight550, PA1803-Dylight594, PA1803-FITC, PA1803-HRP, PA1803-APC, PA1803-PE, PA1803-iFluor647, PA1803-carrier-free
Alternative Names	Transcription factor RelB
Background	RELB (v-rel reticuloendotheliosis viral oncogene homolog B) is also known as IREL. The Inteational Radiation Hybrid Mapping Consortium assigned the RELB gene to chromosome 19. By RT-PCR and immunocytochemical analyses, Clark et al. (1999) showed that RELB expression correlated with dendritic cell activation. NF-kappa-B-inducing kinase is required for osteoclastogenesis in response to pathologic stimuli. Vaira et al. (2008) found that overexpression of Relb, but not Rela, rescued differentiation of mouse Nik -/- osteoclast precursors, indicating that blockade of the alteative NF-kappa-B pathway, rather than the classical NF-kappa-B pathway, is responsible for the osteoclastogenic defect in the absence of Nik. Using Relb -/- mice, they showed that Relb itself was required for Rankl-induced osteoclastogenesis in vitro and for TNF-induced bone resorption in vivo. Both Relb -/- and Nik -/- mice were resistant to tumor-mediated osteolysis. Vaira et al. (2008) concluded that the alteative NF-kappa-B pathway, via RELB, plays an essential and unique role in RANKL signaling toward osteoclast development.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Rel B/RELB Antibody catalog # PA1803. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or he
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human Rel B, identical to the related mouse sequence.
Isotype	Rabbit IgG
Molecular Weight	23 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Transcription factor RelB;I-Rel;RELB;
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q01201
Gene Name	RELB
Sequence	Contains 1 RHD (Rel-like) domain.
Subcellular Location	Nucleus . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Colocalizes with NEK6 in the centrosome.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Mouse, Rat<br>

Reference	1. Clark, G. J., Gunningham, S., Troy, A., Vuckovic, S., Hart, D. N.Expression of the RelB transcription factor correlates with the activation of human dendritic cells.Immunology 98: 189-196, 1999.<br /><br />2. Ruben, S. M., Klement, J. F., Coleman, T. A., Maher, M., Chen, C.-H., Rosen, C. A.I-Rel: a novel rel-related protein that inhibits NF-kappa-B transcriptional activity.Genes Dev. 6: 745-760, 1992.<br /><br />3. Vaira, S., Johnson, T., Hirbe, A. C., Alhawagri, M., Anwisye, I., Sammut, B., O'Neal, J., Zou, W., Weilbaecher, K. N., Faccio, R., Novack, D. V. RelB is the NF-kappa-B subunit downstream of NIK responsible for osteoclast differentiation.Proc. Nat. Acad. Sci. 105: 3897-3902, 2008.<br /><br />

Have you used this product?

Rate it now..!!

Login to Review

Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007071-1	PA1803	-	100 ug	$370		Add to Cart
BHA21007071-2	PA1803-10ug	Sample	10 ug	$99		Add to Cart
BHA21007071-3	PA1803-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007071-4	PA1803-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007071-5	PA1803-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007071-6	PA1803-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007071-7	PA1803-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007071-8	PA1803-FITC	FITC	100 ug	$570		Add to Cart
BHA21007071-9	PA1803-HRP	HRP	100 ug	$570		Add to Cart
BHA21007071-10	PA1803-APC	APC	100 ug	$670		Add to Cart
BHA21007071-11	PA1803-PE	PE	100 ug	$670		Add to Cart
BHA21007071-12	PA1803-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007071-13	PA1803-carrier-free	carrier-free	100 ug	$370		Add to Cart

ebiohippo.com provides biomedical researchers with a one-stop informatic shopping experience by transforming biotechnology products’ data into a ready-to-analyze state. We collect and unify suppliers’ data on a single platform to reduce the time of searching, uncertainty, and cost of scientific experiments.

© 2025 Biohippo. All rights reserved.