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Home / Primary Antibodies / Polyclonal Antibodies

Anti-RAB3GAP2 Antibody Picoband®

SKU : BHA21002197

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Mfr.No.	A07244-3, A07244-3-10ug, A07244-3-Biotin, A07244-3-Cy3, A07244-3-Dylight488, A07244-3-Dylight550, A07244-3-Dylight594, A07244-3-FITC, A07244-3-HRP, A07244-3-APC, A07244-3-PE, A07244-3-iFluor647, A07244-3-carrier-free
Alternative Names	RAB3 GTPase activating non-catalytic protein subunit 2
Background	Rab3 GTPase-activating protein non-catalytic subunit is an enzyme that in humans is encoded by the RAB3GAP2 gene. It is mapped to 1q41. The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-RAB3GAP2 Antibody Picoband® catalog # A07244-3. Tested in ELISA, IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically co
Host	Rabbit
Immunogen Region	E.coli-derived human RAB3GAP2 recombinant protein (Position: M1-Q115).
Isotype	Rabbit IgG
Molecular Weight	156 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Rab3 GTPase-activating protein non-catalytic subunit; RGAP-iso; Rab3 GTPase-activating protein 150 kDa subunit; Rab3-GAP p150; Rab3-GAP150; Rab3-GAP regulatory subunit; RAB3GAP2; KIAA0839
Tissue Specificity	Ubiquitous.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q9H2M9
Gene Id	25782
Gene Name	RAB3GAP2
Subcellular Location	Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IHC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Borck, G., Wunram, H., Steiert, A., Volk, A. E., Korber, F., Roters, S., Herkenrath, P., Wollnik, B., Morris-Rosendahl, D. J., Kubisch, C. A homozygous RAB3GAP2 mutation causes Warburg Micro syndrome. Hum. Genet. 129: 45-50, 2011.<br /><br />2. Handley, M. T., Morris-Rosendahl, D. J., Brown, S., Macdonald, F., Hardy, C., Bem, D., Carpanini, S. M., Borck, G., Martorell, L., Izzi, C., Faravelli, F., Accorsi, P., and 23 others. Mutation spectrum in RAB3GAP1, RAB3GAP2, and RAB18 and genotype-phenotype correlations in Warburg Micro syndrome and Martsolf syndrome. Hum. Mutat. 34: 686-696, 2013.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002197-1	A07244-3	-	100 ug	$370		Add to Cart
BHA21002197-2	A07244-3-10ug	Sample	10 ug	$99		Add to Cart
BHA21002197-3	A07244-3-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002197-4	A07244-3-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002197-5	A07244-3-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002197-6	A07244-3-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002197-7	A07244-3-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002197-8	A07244-3-FITC	FITC	100 ug	$570		Add to Cart
BHA21002197-9	A07244-3-HRP	HRP	100 ug	$570		Add to Cart
BHA21002197-10	A07244-3-APC	APC	100 ug	$670		Add to Cart
BHA21002197-11	A07244-3-PE	PE	100 ug	$670		Add to Cart
BHA21002197-12	A07244-3-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002197-13	A07244-3-carrier-free	carrier-free	100 ug	$370		Add to Cart

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