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Home / Primary Antibodies / Polyclonal Antibodies

Anti-QPRT Antibody Picoband®

SKU : BHA21004971

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Mfr.No.	A09896, A09896-10ug, A09896-Biotin, A09896-Cy3, A09896-Dylight488, A09896-Dylight550, A09896-Dylight594, A09896-FITC, A09896-HRP, A09896-APC, A09896-PE, A09896-iFluor647, A09896-carrier-free
Alternative Names	interleukin 36, alpha
Background	This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-QPRT Antibody Picoband® catalog # A09896. Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Cytokine that binds to and signals through the IL1RL2/IL-36R receptor which in tu activates NF-kappa-B and MAPK signaling pathways in target cells linked to a pro-inflammatory response. Part of the IL-36 signaling system that is thought to be present in
Host	Rabbit
Immunogen Region	E.coli-derived human QPRT recombinant protein (Position: R24-H297).
Isotype	Rabbit IgG
Molecular Weight	31-35 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Interleukin-36 alpha; FIL1 epsilon; Interleukin-1 epsilon; IL-1 epsilon; Interleukin-1 family member 6; IL-1F6; IL36A; FIL1E; IL1E; IL1F6
Tissue Specificity	Expressed in immune system and fetal brain, but not in other tissues tested or in multiple hematopoietic cell lines. Predominantly expressed in skin keratinocytes but not in fibroblasts, endothelial cells or melanocytes. Increased in lesional psoriasis skin.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q15274
Gene Id	23475
Gene Name	QPRT
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Fukuoka, S.-I., Nyaruhucha, C. M., Shibata, K. Characterization and functional expression of the cDNA encoding human brain quinolinate phosphoribosyltransferase. Biochim. Biophys. Acta 1395: 192-201, 1998.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21004971-1	A09896	-	100 ug	$370		Add to Cart
BHA21004971-2	A09896-10ug	Sample	10 ug	$99		Add to Cart
BHA21004971-3	A09896-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21004971-4	A09896-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21004971-5	A09896-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21004971-6	A09896-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21004971-7	A09896-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21004971-8	A09896-FITC	FITC	100 ug	$570		Add to Cart
BHA21004971-9	A09896-HRP	HRP	100 ug	$570		Add to Cart
BHA21004971-10	A09896-APC	APC	100 ug	$670		Add to Cart
BHA21004971-11	A09896-PE	PE	100 ug	$670		Add to Cart
BHA21004971-12	A09896-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21004971-13	A09896-carrier-free	carrier-free	100 ug	$370		Add to Cart

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