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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PRUNE1 Antibody Picoband®

SKU : BHA21005392

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Mfr.No.	A31798, A31798-10ug, A31798-Biotin, A31798-Cy3, A31798-Dylight488, A31798-Dylight550, A31798-Dylight594, A31798-FITC, A31798-HRP, A31798-APC, A31798-PE, A31798-iFluor647, A31798-carrier-free
Alternative Names	retrotransposon Gag like 10
Background	This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PRUNE1 Antibody Picoband® catalog # A31798. Tested in ELISA, IF, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Could induce apoptosis in a BH3 domain-dependent manner. The interaction network of Bcl-2 family members may play a key role in modulation RTL10/BOP intrinsic apoptotic signaling activity.
Host	Rabbit
Immunogen Region	E.coli-derived human PRUNE1 recombinant protein (Position: M1-Q444).
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Protein Bop; BH3-only protein; Retrotransposon Gag-like protein 10; RTL10; BOP, C22orf29
Tissue Specificity	Ubiquitously expressed.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q86TP1
Gene Id	58497
Gene Name	PRUNE1
Subcellular Location	Cell membrane; Lipid-anchor, GPI-anchor.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Alhaddad, B., Schossig, A., Haack, T. B., Kovacs-Nagy, R., Braunisch, M. C., Makowski, C., Senderek, J., Vill, K., Muller-Felber, W., Strom, T. M., Krabichler, B., Freisinger, P., and 17 others. PRUNE1 deficiency: expanding the clinical and genetic spectrum. Neuropediatrics 49: 330-338, 2018. <br /><br />2. Costain, G., Shugar, A., Krishnan, P., Mahmutoglu, S., Laughlin, S., Kannu, P. Homozygous mutation in PRUNE1 in an Oji-Cree male with a complex neurological phenotype. Am. J. Med. Genet. 173A: 740-743, 2017.<br /><br />3. Diana, D., Smaldone, G., De Antonellis, P., Pirone, L., Carotenuto, M., Alonzi, A., Di Gaetano, S., Zollo, M., Pedone, E. M., Fattorusso, R. Mapping functional interaction sites of human prune C-terminal domain by NMR spectroscopy in human cell lysates. Chemistry 19: 12217-12220, 2013.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005392-1	A31798	-	100 ug	$370		Add to Cart
BHA21005392-2	A31798-10ug	Sample	10 ug	$99		Add to Cart
BHA21005392-3	A31798-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005392-4	A31798-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005392-5	A31798-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005392-6	A31798-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005392-7	A31798-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005392-8	A31798-FITC	FITC	100 ug	$570		Add to Cart
BHA21005392-9	A31798-HRP	HRP	100 ug	$570		Add to Cart
BHA21005392-10	A31798-APC	APC	100 ug	$670		Add to Cart
BHA21005392-11	A31798-PE	PE	100 ug	$670		Add to Cart
BHA21005392-12	A31798-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005392-13	A31798-carrier-free	carrier-free	100 ug	$370		Add to Cart

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