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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband®

SKU : BHA21000993

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Mfr.No.	PB10088, PB10088-10ug, PB10088-Biotin, PB10088-Cy3, PB10088-Dylight488, PB10088-Dylight550, PB10088-Dylight594, PB10088-FITC, PB10088-HRP, PB10088-APC, PB10088-PE, PB10088-iFluor647, PB10088-carrier-free
Alternative Names	Proteasome subunit alpha type-2
Background	Proteasome subunit alpha type-2 is a protein that in humans is encoded by the PSMA2 gene. The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Proteasome 20S alpha 2/PSMA2 Antibody Picoband® catalog # PB10088. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human PSMA2, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	26 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Proteasome subunit alpha type-2;3.4.25.1;Macropain subunit C3;Multicatalytic endopeptidase complex subunit C3;Proteasome component C3;PSMA2;HC3, PSC3;
Tissue Specificity	Expressed at high levels in the brain, liver, kidney and pancreas, and very weakly expressed in the thymus, prostate, testis and colon.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P25787
Gene Id	5683
Gene Name	PSMA2
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, P-body . Colocalizes with TRIM5 in the cytoplasmic bodies. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. Groll M, Ditzel L, Löwe J, Stock D, Bochtler M, Bartunik HD, Huber R (Apr 1997). "Structure of 20S proteasome from yeast at 2.4 A resolution". Nature 386 (6624): 46371. 2. Tomko RJ, Hochstrasser M (2013). "Molecular architecture and assembly of the eukaryotic proteasome". Annual Review of Biochemistry 82: 41545.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000993-1	PB10088	100 ug	-	$370		Add to Cart
BHA21000993-2	PB10088-10ug	10 ug	Sample	$99		Add to Cart
BHA21000993-3	PB10088-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000993-4	PB10088-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000993-5	PB10088-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000993-6	PB10088-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000993-7	PB10088-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000993-8	PB10088-FITC	100 ug	FITC	$570		Add to Cart
BHA21000993-9	PB10088-HRP	100 ug	HRP	$570		Add to Cart
BHA21000993-10	PB10088-APC	100 ug	APC	$670		Add to Cart
BHA21000993-11	PB10088-PE	100 ug	PE	$670		Add to Cart
BHA21000993-12	PB10088-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000993-13	PB10088-carrier-free	100 ug	carrier-free	$370		Add to Cart

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