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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Prokineticin 1/PROK1 Antibody Picoband®

SKU : BHA21000782

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Mfr.No.	PB9882, PB9882-10ug, PB9882-Biotin, PB9882-Cy3, PB9882-Dylight488, PB9882-Dylight550, PB9882-Dylight594, PB9882-FITC, PB9882-HRP, PB9882-APC, PB9882-PE, PB9882-iFluor647, PB9882-carrier-free
Alternative Names	Prokineticin-1
Background	Prokineticin-1 is also known as EG-VEGF. The International Radiation Hybrid Mapping Consortium mapped the PROK1 gene to chromosome 1. The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Prokineticin 1/PROK1 Antibody Picoband® catalog # PB9882. Tested in WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells. Induces proliferation and differentiation, but not migration, of enteric
Host	Rabbit
Immunogen Region	E. coli-derived mouse Prokineticin 1 recombinant protein (Position: A20-F105). Mouse Prokineticin 1 shares 88.4% and 94.2% amino acid (aa) sequence identity with human and rat Prokineticin 1, respectively.
Isotype	Rabbit IgG
Molecular Weight	12 kDa
Reactivity	Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Prokineticin-1 ;Endocrine-gland-derived vascular endothelial growth factor ;EG-VEGF ;Prok1 ;Pk1 ;
Tissue Specificity	Highly expressed in liver and ovary and weakly expressed in testis and placenta. Expressed in mucosa and mesenchyme of embryonic gut during enteric nervous system development (at protein level). Predominantly expressed in kidney and liver. Also expressed in lung, ovary, placenta and testis. In fetal liver, is restricted to and highly expressed in hepatocytes. In adult kidney, expression is restricted to the endothelial tubule cells. In placenta, expressed throughout gestation. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q14A28
Gene Id	246691
Gene Name	PROK1
Subcellular Location	Secreted .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Western blot, 0.1-0.5ug/ml, Mouse

Reference	1. LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G., Rangell, L., DeGuzman, L., Keller, G.-A., Peale, F., Gurney, P., Hillan, K. J., Ferrara, N. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 412: 877-884, 2001. 2. Li, M., Bullock, C. M., Knauer, D. J., Ehlert, F. J., Zhou, Q. Y. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Molec. Pharm. 59: 692-698, 2001.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000782-1	PB9882	100 ug	-	$370		Add to Cart
BHA21000782-2	PB9882-10ug	10 ug	Sample	$99		Add to Cart
BHA21000782-3	PB9882-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000782-4	PB9882-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000782-5	PB9882-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000782-6	PB9882-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000782-7	PB9882-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000782-8	PB9882-FITC	100 ug	FITC	$570		Add to Cart
BHA21000782-9	PB9882-HRP	100 ug	HRP	$570		Add to Cart
BHA21000782-10	PB9882-APC	100 ug	APC	$670		Add to Cart
BHA21000782-11	PB9882-PE	100 ug	PE	$670		Add to Cart
BHA21000782-12	PB9882-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000782-13	PB9882-carrier-free	100 ug	carrier-free	$370		Add to Cart

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