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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Prokineticin 1/PROK1 Antibody Picoband®

SKU : BHA21000783

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Mfr.No.	PB9881, PB9881-10ug, PB9881-Biotin, PB9881-Cy3, PB9881-Dylight488, PB9881-Dylight550, PB9881-Dylight594, PB9881-FITC, PB9881-HRP, PB9881-APC, PB9881-PE, PB9881-iFluor647, PB9881-carrier-free
Alternative Names	Prokineticin-1
Background	Prokineticin-1 is also known as EG-VEGF. The Inteational Radiation Hybrid Mapping Consortium mapped the PROK1 gene to chromosome 1. The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Prokineticin 1/PROK1 Antibody Picoband® catalog # PB9881. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of oth
Host	Rabbit
Immunogen Region	E. coli-derived human Prokineticin 1 recombinant protein (Position: A20-F105). Human Prokineticin 1 shares 88.4% and 91.9% amino acid (aa) sequence identity with mouse and rat Prokineticin 1, respectively.
Isotype	Rabbit IgG
Molecular Weight	20 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Prokineticin-1;Endocrine-gland-derived vascular endothelial growth factor;EG-VEGF;Mambakine;PROK1;UNQ600/PRO1186;
Tissue Specificity	Localizes to glandular epithelium, stroma and vascular epithelial cells of first trimester decidua (at protein level). Up-regulated in first trimester decidua when compared with non-pregnant endometrium. Expressed in the steroidogenic glands, ovary, testis, adrenal and placenta. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P58294
Gene Id	84432
Gene Name	PROK1
Subcellular Location	Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, WB
Description	ELISA, 0.1-0.5ug/ml, - Weste blot, 0.1-0.5ug/ml, Human

Reference	1. LeCouter, J., Kowalski, J., Foster, J., Hass, P., Zhang, Z., Dillard-Telm, L., Frantz, G., Rangell, L., DeGuzman, L., Keller, G.-A., Peale, F., Guey, P., Hillan, K. J., Ferrara, N. Identification of an angiogenic mitogen selective for endocrine gland endothelium. Nature 412: 877-884, 2001. 2. Li, M., Bullock, C. M., Knauer, D. J., Ehlert, F. J., Zhou, Q. Y. Identification of two prokineticin cDNAs: recombinant proteins potently contract gastrointestinal smooth muscle. Molec. Pharm. 59: 692-698, 2001.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000783-1	PB9881	100 ug	-	$370		Add to Cart
BHA21000783-2	PB9881-10ug	10 ug	Sample	$99		Add to Cart
BHA21000783-3	PB9881-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000783-4	PB9881-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000783-5	PB9881-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000783-6	PB9881-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000783-7	PB9881-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000783-8	PB9881-FITC	100 ug	FITC	$570		Add to Cart
BHA21000783-9	PB9881-HRP	100 ug	HRP	$570		Add to Cart
BHA21000783-10	PB9881-APC	100 ug	APC	$670		Add to Cart
BHA21000783-11	PB9881-PE	100 ug	PE	$670		Add to Cart
BHA21000783-12	PB9881-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000783-13	PB9881-carrier-free	100 ug	carrier-free	$370		Add to Cart

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