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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PPM1E Picoband® Antibody

SKU : BHA21002563

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Mfr.No.	A08794, A08794-10ug, A08794-Biotin, A08794-Cy3, A08794-Dylight488, A08794-Dylight550, A08794-Dylight594, A08794-FITC, A08794-HRP, A08794-APC, A08794-PE, A08794-iFluor647, A08794-carrier-free
Alternative Names	protein phosphatase, Mg2+/Mn2+ dependent 1E
Background	protein phosphatase, Mg2+/Mn2+ dependent 1E is a protein that in humans is encoded by the PPM1E gene. It is mapped to 17q22. This gene encodes a member of the PPM family of serine/threonine-protein phosphatases. The encoded protein is localized to the nucleus and dephosphorylates and inactivates multiple substrates including serine/threonine-protein kinase PAK 1, 5'-AMP-activated protein kinase (AMPK) and the multifunctional calcium/calmodulin-dependent protein kinases. Alteatively spliced transcript variants have been observed for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PPM1E Picoband® Antibody catalog # A08794. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Protein phosphatase that inactivates multifunctional CaM kinases such as CAMK4 and CAMK2. Dephosphorylates and inactivates PAK. May play a role in the inhibition of actin fiber stress breakdown and in morphological changes driven by TNK2/CDC42. Dephosphor
Host	Rabbit
Immunogen Region	E.coli-derived human PPM1E recombinant protein (Position: E141-E755).
Isotype	Rabbit IgG
Molecular Weight	84 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Protein phosphatase 1E; Ca (2+)/calmodulin-dependent protein kinase phosphatase N; CaMKP-N; CaMKP-nucleus; CaMKN; Partner of PIX 1; Partner of PIX-alpha; Partner of PIXA; PPM1E; CAMKN; KIAA1072; POPX1
Tissue Specificity	Expressed in fetal and adult brain. Also detected in fetal liver and skeletal muscle, but not in their adult counterparts.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na<sub>2</sub>HPO<sub>4</sub>, 0.05mg NaN<sub>3</sub>.

Uniprot	Q8WY54
Gene Id	22843
Gene Name	PPM1E
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 2ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002563-1	A08794	-	100 ug	$370		Add to Cart
BHA21002563-2	A08794-10ug	Sample	10 ug	$99		Add to Cart
BHA21002563-3	A08794-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002563-4	A08794-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002563-5	A08794-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002563-6	A08794-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002563-7	A08794-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002563-8	A08794-FITC	FITC	100 ug	$570		Add to Cart
BHA21002563-9	A08794-HRP	HRP	100 ug	$570		Add to Cart
BHA21002563-10	A08794-APC	APC	100 ug	$670		Add to Cart
BHA21002563-11	A08794-PE	PE	100 ug	$670		Add to Cart
BHA21002563-12	A08794-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002563-13	A08794-carrier-free	carrier-free	100 ug	$370		Add to Cart

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