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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PPFIA2 Antibody Picoband®

SKU : BHA21005408

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Mfr.No.	A11773, A11773-10ug, A11773-Biotin, A11773-Cy3, A11773-Dylight488, A11773-Dylight550, A11773-Dylight594, A11773-FITC, A11773-HRP, A11773-APC, A11773-PE, A11773-iFluor647, A11773-carrier-free
Alternative Names	eva-1 homolog A, regulator of programmed cell death
Background	The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alteative splicing results in multiple transcript variants
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PPFIA2 Antibody Picoband® catalog # A11773. Tested in ELISA, IHC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Acts as a regulator of programmed cell death, mediating both autophagy and apoptosis.
Host	Rabbit
Immunogen Region	E.coli-derived human PPFIA2 recombinant protein (Position: E221-C1257).
Isotype	Rabbit IgG
Molecular Weight	143 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Protein eva-1 homolog A; Protein FAM176A; Transmembrane protein 166; EVA1A; FAM176A; TMEM166; SP24
Tissue Specificity	Expressed in lung, kidney, liver, pancreas, placenta, but not in heart and skeletal muscle.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	O75334
Gene Id	8499
Gene Name	PPFIA2
Subcellular Location	Endoplasmic reticulum membrane, Single-pass membrane protein, Lysosome membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Mouse, Rat<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Gross, M. B. Personal Communication. Baltimore, Md. 9/2/2022.<br /><br />2. Serra-Pages, C., Medley, Q. G., Tang, M., Hart, A., Streuli, M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273: 15611-15620, 1998. <br /><br />3. Stucchi, R., Plucinska, G., Hummel, J. J. A., Zahavi, E. E., Guerra San Juan, I., Klykov, O., Scheltema, R. A., Maarten Altelaar, A. F., Hoogenraad, C. C. Regulation of KIF1A-driven dense core vesicle transport: Ca(2+)/CaM controls DCV binding and liprin-alpha/TANC2 recruits DCVs to postsynaptic sites. Cell Rep. 24: 685-700, 2018.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005408-1	A11773	-	100 ug	$370		Add to Cart
BHA21005408-2	A11773-10ug	Sample	10 ug	$99		Add to Cart
BHA21005408-3	A11773-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005408-4	A11773-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005408-5	A11773-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005408-6	A11773-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005408-7	A11773-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005408-8	A11773-FITC	FITC	100 ug	$570		Add to Cart
BHA21005408-9	A11773-HRP	HRP	100 ug	$570		Add to Cart
BHA21005408-10	A11773-APC	APC	100 ug	$670		Add to Cart
BHA21005408-11	A11773-PE	PE	100 ug	$670		Add to Cart
BHA21005408-12	A11773-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005408-13	A11773-carrier-free	carrier-free	100 ug	$370		Add to Cart

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