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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PPA2 Antibody Picoband®

SKU : BHA21002195

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Mfr.No.	A06587, A06587-10ug, A06587-Biotin, A06587-Cy3, A06587-Dylight488, A06587-Dylight550, A06587-Dylight594, A06587-FITC, A06587-HRP, A06587-APC, A06587-PE, A06587-iFluor647, A06587-carrier-free
Alternative Names	pyrophosphatase (inorganic) 2
Background	Inorganic pyrophosphatase 2, mitochondrial is is a protein that in humans is encoded by the PPA2 gene. It is mapped to 4q24. The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alteate transcriptional splice variants, encoding different isoforms, have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PPA2 Antibody Picoband® catalog # A06587. Tested in ELISA, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Hydrolyzes inorganic pyrophosphate. This activity is essential for correct regulation of mitochondrial membrane potential, and mitochondrial organization and function.
Host	Rabbit
Immunogen Region	E.coli-derived human PPA2 recombinant protein (Position: A33-K334).
Isotype	Rabbit IgG
Molecular Weight	38 kDa
Reactivity	Human, Mouse
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Inorganic pyrophosphatase 2, mitochondrial; Pyrophosphatase SID6-306; Pyrophosphate phospho-hydrolase 2; PPase 2; PPA2; HSPC124
Tissue Specificity	Detected in brain, gastric carcinoma, lung, ovary, skeletal muscle, umbilical cord blood and a cell line derived from kidney proximal tubule epithelium.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q9H2U2
Gene Id	27068
Gene Name	PPA2
Subcellular Location	Mitochondrion.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml<br> Immunohistochemistry, 2-5 ug/ml<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml<br> ELISA, 0.1-0.5ug/ml<br>

Reference	1. Guimier, A., Gordon, C. T., Godard, F., Ravenscroft, G., Oufadem, M., Vasnier, C., Rambaud, C., Nitschke, P., Bole-Feysot, C., Masson, C., Dauger, S., Longman, C., and 15 others. Biallelic PPA2 mutations cause sudden unexpected cardiac arrest in infancy. Am. J. Hum. Genet. 99: 666-673, 2016. <br /><br />2. Kennedy, H., Haack, T. B., Hartill, V., Matakovic, L., Baumgartner, E. R., Potter, H., Mackay, R., Alston, C. L., O'Sullivan, S., McFarland, R., Connolly, G., Gannon, C., and 23 others. Sudden cardiac death due to deficiency of the mitochondrial inorganic pyrophosphatase PPA2. Am. J. Hum. Genet. 99: 674-682, 2016.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002195-1	A06587	-	100 ug	$370		Add to Cart
BHA21002195-2	A06587-10ug	Sample	10 ug	$99		Add to Cart
BHA21002195-3	A06587-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002195-4	A06587-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002195-5	A06587-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002195-6	A06587-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002195-7	A06587-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002195-8	A06587-FITC	FITC	100 ug	$570		Add to Cart
BHA21002195-9	A06587-HRP	HRP	100 ug	$570		Add to Cart
BHA21002195-10	A06587-APC	APC	100 ug	$670		Add to Cart
BHA21002195-11	A06587-PE	PE	100 ug	$670		Add to Cart
BHA21002195-12	A06587-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002195-13	A06587-carrier-free	carrier-free	100 ug	$370		Add to Cart

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