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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody

SKU : BHA21002557

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Mfr.No.	A01624, A01624-10ug, A01624-Biotin, A01624-Cy3, A01624-Dylight488, A01624-Dylight550, A01624-Dylight594, A01624-FITC, A01624-HRP, A01624-APC, A01624-PE, A01624-iFluor647, A01624-carrier-free
Alternative Names	polymeric immunoglobulin receptor
Background	Polymeric immunoglobulin receptor (pIgR) is a transmembrane protein that in humans is encoded by the PIGR gene. It is mapped to 1 E4; 1 56.89 cM. This gene is a member of the immunoglobulin superfamily. The encoded poly-Ig receptor binds polymeric immunoglobulin molecules at the basolateral surface of epithelial cells; the complex is then transported across the cell to be secreted at the apical surface. A significant association was found between immunoglobulin A nephropathy and several SNPs in this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Polymeric immunoglobulin receptor/PIGR Picoband® Antibody catalog # A01624. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	This receptor binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known a
Host	Rabbit
Immunogen Region	E.coli-derived mouse Polymeric immunoglobulin receptor/PIGR recombinant protein (Position: D34-A771).
Isotype	Rabbit IgG
Molecular Weight	85-100 kDa
Reactivity	Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Polymeric immunoglobulin receptor; PIgR; Poly-Ig receptor; Secretory component; Pigr
Tissue Specificity	Expressed in all tissues examined.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	O70570
Gene Id	18703
Gene Name	Pigr
Subcellular Location	Cell membrane. Single-pass type I membrane protein. Secreted.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, WB
Description	Weste blot, 0.25-0.5ug/ml, Mouse, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Rat<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Davidson, M. K., Le Beau, M. M., Eddy, R. L., Shows, T. B., DiPietro, L. A., Kingzette, M., Hanly, W. C. Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31-q41. Cytogenet. Cell Genet. 48: 107-111, 1988. <br /><br />2. Hood, L., Kronenberg, M., Hunkapiller, T. T cell antigen receptors and the immunoglobulin supergene family. Cell 40: 225-229, 1985.<br /><br />3. Krajci, P., Gedde-Dahl, T., Jr., Hoyheim, B., Rogde, S., Olaisen, B., Brandtzaeg, P. The gene encoding human transmembrane secretory component (locus PIGR) is linked to D1S58 on chromosome 1. Hum. Genet. 90: 215-219, 1992.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002557-1	A01624	-	100 ug	$370		Add to Cart
BHA21002557-2	A01624-10ug	Sample	10 ug	$99		Add to Cart
BHA21002557-3	A01624-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002557-4	A01624-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002557-5	A01624-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002557-6	A01624-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002557-7	A01624-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002557-8	A01624-FITC	FITC	100 ug	$570		Add to Cart
BHA21002557-9	A01624-HRP	HRP	100 ug	$570		Add to Cart
BHA21002557-10	A01624-APC	APC	100 ug	$670		Add to Cart
BHA21002557-11	A01624-PE	PE	100 ug	$670		Add to Cart
BHA21002557-12	A01624-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002557-13	A01624-carrier-free	carrier-free	100 ug	$370		Add to Cart

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