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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Poliovirus Receptor/PVR Antibody Picoband®

SKU : BHA21003205

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Mfr.No.	A00664-2, A00664-2-10ug, A00664-2-Biotin, A00664-2-Cy3, A00664-2-Dylight488, A00664-2-Dylight550, A00664-2-Dylight594, A00664-2-FITC, A00664-2-HRP, A00664-2-APC, A00664-2-PE, A00664-2-iFluor647, A00664-2-carrier-free
Alternative Names	killer cell lectin like receptor K1
Background	CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The exteal domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-Poliovirus Receptor/PVR Antibody Picoband® catalog # A00664-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Function as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress-inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costim
Host	Rabbit
Immunogen Region	E.coli-derived human Poliovirus Receptor/PVR recombinant protein (Position: D28-E331).
Isotype	Rabbit IgG
Molecular Weight	70-80 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	NKG2-D type II integral membrane protein; Killer cell lectin-like receptor subfamily K member 1; NK cell receptor D; NKG2-D-activating NK receptor; CD314; KLRK1; D12S2489E; NKG2D
Tissue Specificity	Expressed in natural killer (NK) cells, CD8 (+) alpha-beta and gamma-delta T-cells. Expressed on essentially all CD56+CD3- NK cells from freshly isolated PBMC. Expressed in interferon-producing killer dendritic cells (IKDCs).
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	P15151
Gene Id	5817
Gene Name	PVR
Subcellular Location	Cell membrane.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.1-0.25ug/ml, Human<br> Immunohistochemistry (Paraffin-embedded Section), 1-2ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Bottino, C., Castriconi, R., Pende, D., Rivera, P., Nanni, M., Caemolla, B., Cantoni, C., Grassi, J., Marcenaro, S., Reymond, N., Vitale, M., Moretta, L., Lopez, M., Moretta, A. Identification of PVR (CD155) and nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule. J. Exp. Med. 198: 557-567, 2003.<br /><br />2. Fuchs, A., Cella, M., Giurisato, E., Shaw, A. S., Colonna, M. Cutting edge: CD96 (tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J. Immun. 172: 3994-3998, 2004.<br /><br />3. Gromeier, M., Solecki, D., Patel, D. D., Wimmer, E. Expression of the human poliovirus receptor/CD155 gene during development of the central nervous system: implications for the pathogenesis of poliomyelitis. Virology 273: 248-257, 2000. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003205-1	A00664-2	-	100 ug	$370		Add to Cart
BHA21003205-2	A00664-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003205-3	A00664-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003205-4	A00664-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003205-5	A00664-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003205-6	A00664-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003205-7	A00664-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003205-8	A00664-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003205-9	A00664-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003205-10	A00664-2-APC	APC	100 ug	$670		Add to Cart
BHA21003205-11	A00664-2-PE	PE	100 ug	$670		Add to Cart
BHA21003205-12	A00664-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003205-13	A00664-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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