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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Plzf/ZBTB16 Antibody Picoband®

SKU : BHA21000868

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Mfr.No.	PB9969, PB9969-10ug, PB9969-Biotin, PB9969-Cy3, PB9969-Dylight488, PB9969-Dylight550, PB9969-Dylight594, PB9969-FITC, PB9969-HRP, PB9969-APC, PB9969-PE, PB9969-iFluor647, PB9969-carrier-free
Alternative Names	Zinc finger and BTB domain-containing protein 16
Background	Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene. This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alteate transcriptional splice variants have been characterized.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Plzf/ZBTB16 Antibody Picoband® catalog # PB9969. Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Probable transcription factor. May play a role in myeloid maturation and in the development and/or maintenance of other differentiated tissues. Probable substrate-recognition component of an E3 ubiquitin-protein ligase complex which mediates the ubiquitin
Host	Rabbit
Immunogen Region	E.coli-derived human Plzf recombinant protein (Position: M1-E165).
Isotype	Rabbit IgG
Molecular Weight	74 kDa
Reactivity	Human, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Zinc finger and BTB domain-containing protein 16;Promyelocytic leukemia zinc finger protein;Zinc finger protein 145;Zinc finger protein PLZF;ZBTB16;PLZF, ZNF145;
Tissue Specificity	Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	Q05516
Gene Id	7704
Gene Name	ZBTB16
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB
Description	Weste blot, 0.1-0.5ug/ml, Human, Rat

Reference	1. Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, et al. (2008). "The BTB-zinc finger transcriptional regulator, PLZF, controls the development of iNKT cell effector functions". Nature Immunology 9 (9): 105564. 2. Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, Lantz O, Bendelac A (2008). "The transcription factor PLZF (Zbtb16) s the effector program of the NKT cell lineage".Immunity 29 (3): 391403. 3. Zhang T, Xiong H, Kan LX, Zhang CK, Jiao XF, Fu G, Zhang QH, Lu L, et al. (1999). "Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene".Proceedings of the National Academy of Sciences of the United States of America 96 (20): 114227.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000868-1	PB9969	100 ug	-	$370		Add to Cart
BHA21000868-2	PB9969-10ug	10 ug	Sample	$99		Add to Cart
BHA21000868-3	PB9969-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000868-4	PB9969-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000868-5	PB9969-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000868-6	PB9969-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000868-7	PB9969-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000868-8	PB9969-FITC	100 ug	FITC	$570		Add to Cart
BHA21000868-9	PB9969-HRP	100 ug	HRP	$570		Add to Cart
BHA21000868-10	PB9969-APC	100 ug	APC	$670		Add to Cart
BHA21000868-11	PB9969-PE	100 ug	PE	$670		Add to Cart
BHA21000868-12	PB9969-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000868-13	PB9969-carrier-free	100 ug	carrier-free	$370		Add to Cart

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