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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PLS3 Antibody Picoband®

SKU : BHA21006312

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Mfr.No.	A04134-1, A04134-1-10ug, A04134-1-Biotin, A04134-1-Cy3, A04134-1-Dylight488, A04134-1-Dylight550, A04134-1-Dylight594, A04134-1-FITC, A04134-1-HRP, A04134-1-APC, A04134-1-PE, A04134-1-iFluor647, A04134-1-carrier-free
Background	Plastin-3 is a highly conserved protein that in humans is encoded by the PLS3 gene on the X chromosome. Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). The C-terminal 570 amino acids of the T-plastin and L-plastin proteins are 83% identical. It contains a potential calcium-binding site near the N terminus. Alteate splicing results in multiple transcript variants.
Clonality	Polyclonal
Description	Boster Bio Anti-PLS3 Antibody Picoband® catalog # A04134-1. Tested in WB, ICC/IF, IP, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human PLS3 recombinant protein (Position: M1-D580). Human PLS3 shares 99% and 97.9% amino acid (aa) sequence identity with mouse and rat PLS3, respectively.
Molecular Weight	71 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P13797
Gene Id	5358
Gene Name	PLS3

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, IP, IF, ICC, WB
Description	Weste blot, 0.1-0.25 ug/ml, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Immunoprecipitation, 2-4 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Ackermann, B., Krober, S., Torres-Benito, L., Borgmann, A., Peters, M., Barkooie, S. M. H., Tejero, R., Jakubik, M., Schreml, J., Milbradt, J., Wunderlich, T. F., Riessland, M., Tabares, L., Wirth, B. Plastin 3 ameliorates spinal muscular atrophy via delayed axon pruning and improves neuromuscular junction functionality. Hum. Molec. Genet. 22: 1328-1347, 2013. 2. Lin, C.-S., Aebersold, R. H., Kent, S. B., Varma, M., Leavitt, J. Molecular cloning and characterization of plastin, a human leukocyte protein expressed in transformed human fibroblasts. Molec. Cell. Biol. 8: 4659-4668, 1988. 3. Lin, C.-S., Aebersold, R. H., Leavitt, J. Correction of the N-terminal sequences of the human plastin isoforms by using anchored polymerase chain reaction: identification of a potential calcium-binding domain. Molec. Cell. Biol. 10: 1818-1821, 1990.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006312-1	A04134-1	-	100 ug	$370		Add to Cart
BHA21006312-2	A04134-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21006312-3	A04134-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006312-4	A04134-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006312-5	A04134-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006312-6	A04134-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006312-7	A04134-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006312-8	A04134-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21006312-9	A04134-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21006312-10	A04134-1-APC	APC	100 ug	$670		Add to Cart
BHA21006312-11	A04134-1-PE	PE	100 ug	$670		Add to Cart
BHA21006312-12	A04134-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006312-13	A04134-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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