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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PLEKHA1 Antibody Picoband®

SKU : BHA21005243

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Mfr.No.	A08988-1, A08988-1-10ug, A08988-1-Biotin, A08988-1-Cy3, A08988-1-Dylight488, A08988-1-Dylight550, A08988-1-Dylight594, A08988-1-FITC, A08988-1-HRP, A08988-1-APC, A08988-1-PE, A08988-1-iFluor647, A08988-1-carrier-free
Alternative Names	tudor domain containing 3
Background	Pleckstrin homology domain-containing family A member 1 is a protein that in humans is encoded by the PLEKHA1 gene. This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alteate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PLEKHA1 Antibody Picoband® catalog # A08988-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Scaffolding protein that specifically recognizes and binds dimethylarginine-containing proteins. In nucleus, acts as a coactivator: recognizes and binds asymmetric dimethylation on the core histone tails associated with transcriptional activation (H3R17me
Host	Rabbit
Immunogen Region	E.coli-derived human PLEKHA1 recombinant protein (Position: K76-K387).
Isotype	Rabbit IgG
Molecular Weight	46 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	Tudor domain-containing protein 3; TDRD3
Tissue Specificity	Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9HB21
Gene Id	59338
Gene Name	PLEKHA1
Subcellular Location	Nucleus. Cytoplasm.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Conley, Y. P., Jakobsdottir, J., Mah, T., Weeks, D. E., Klein, R., Kuller, L., Ferrell, R. E., Gorin, M. B. CFH, ELOVL4, PLEKHA1 and LOC387715 genes and susceptibility to age-related maculopathy: AREDS and CHS cohorts and meta-analyses. Hum. Molec. Genet. 15: 3206-3218, 2006.<br /><br />2. Dowler, S., Currie, R. A., Campbell, D. G., Deak, M., Kular, G., Downes, C. P., Alessi, D. R. Identification of pleckstrin-homology-domain-containing proteins with novel phosphoinositide-binding specificities. Biochem. J. 351: 19-31, 2000. <br /><br />3. Jakobsdottir, J., Conley, Y. P., Weeks, D. E., Mah, T. S., Ferrell, R. E., Gorin, M. B. Susceptibility genes for age-related maculopathy on chromosome 10q26. Am. J. Hum. Genet. 77: 389-407, 2005.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005243-1	A08988-1	-	100 ug	$370		Add to Cart
BHA21005243-2	A08988-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21005243-3	A08988-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005243-4	A08988-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005243-5	A08988-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005243-6	A08988-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005243-7	A08988-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005243-8	A08988-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21005243-9	A08988-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21005243-10	A08988-1-APC	APC	100 ug	$670		Add to Cart
BHA21005243-11	A08988-1-PE	PE	100 ug	$670		Add to Cart
BHA21005243-12	A08988-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005243-13	A08988-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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