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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PKC eta/PRKCH Antibody Picoband®

SKU : BHA21000452

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Mfr.No.	PB9556, PB9556-10ug, PB9556-Biotin, PB9556-Cy3, PB9556-Dylight488, PB9556-Dylight550, PB9556-Dylight594, PB9556-FITC, PB9556-HRP, PB9556-APC, PB9556-PE, PB9556-iFluor647, PB9556-carrier-free
Alternative Names	Protein kinase C eta type
Background	PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-PKC eta/PRKCH Antibody Picoband® catalog # PB9556. Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Calcium-independent, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that is involved in the regulation of cell differentiation in keratinocytes and pre-B cell receptor, mediates regulation of epithelial tight junction int
Host	Rabbit
Immunogen Region	E.coli-derived human PKC eta recombinant protein (Position: R30-D389). Human PKC eta shares 96.7% and 96.1% amino acid (aa) sequence identity with mouse and rat PKC eta, respectively.
Isotype	Rabbit IgG
Molecular Weight	78 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Protein kinase C eta type;2.7.11.13;PKC-L;nPKC-eta;PRKCH;PKCL, PRKCL;
Tissue Specificity	Most abundant in lung, less in heart and skin. .
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P24723
Gene Id	5583
Gene Name	PRKCH
Sequence	Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
Subcellular Location	Cytoplasm .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	Flow Cytometry, IHC, ICC, WB
Description	Weste blot, 0.1-0.5ug/ml, Human Immunohistochemistry (Frozen Section), 0.5-1ug/ml, Human Immunocytochemistry, 0.5-1ug/ml, Human Flow Cytometry (Fixed), 1-3ug/1x10⁶ cells, Human

Reference	1. "Entrez Gene: PRKCH protein kinase C, eta". 2. Bacher N, Zisman Y, Berent E, Livneh E (Apr 1992). "Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart". Mol Cell Biol 12 (3): 1404.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000452-1	PB9556	100 ug	-	$370		Add to Cart
BHA21000452-2	PB9556-10ug	10 ug	Sample	$99		Add to Cart
BHA21000452-3	PB9556-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000452-4	PB9556-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000452-5	PB9556-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000452-6	PB9556-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000452-7	PB9556-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000452-8	PB9556-FITC	100 ug	FITC	$570		Add to Cart
BHA21000452-9	PB9556-HRP	100 ug	HRP	$570		Add to Cart
BHA21000452-10	PB9556-APC	100 ug	APC	$670		Add to Cart
BHA21000452-11	PB9556-PE	100 ug	PE	$670		Add to Cart
BHA21000452-12	PB9556-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000452-13	PB9556-carrier-free	100 ug	carrier-free	$370		Add to Cart

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