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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PDIA6 Antibody Picoband®

SKU : BHA21003258

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Mfr.No.	A03813-2, A03813-2-10ug, A03813-2-Biotin, A03813-2-Cy3, A03813-2-Dylight488, A03813-2-Dylight550, A03813-2-Dylight594, A03813-2-FITC, A03813-2-HRP, A03813-2-APC, A03813-2-PE, A03813-2-iFluor647, A03813-2-carrier-free
Alternative Names	lon peptidase 1, mitochondrial
Background	This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alteative splicing results in multiple transcript variants encoding different isoforms.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PDIA6 Antibody Picoband® catalog # A03813-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the a
Host	Rabbit
Immunogen Region	E.coli-derived human PDIA6 recombinant protein (Position: L20-L440).
Isotype	Rabbit IgG
Molecular Weight	50 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Synonyms	Lon protease homolog, mitochondrial; LONHs; Lon protease-like protein; LONP; Mitochondrial ATP-dependent protease Lon; Serine protease 15; LONP1; PRSS15
Tissue Specificity	Duodenum, heart, lung and liver, but not thymus.
Note	Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Uniprot	Q15084
Gene Id	10130
Gene Name	PDIA6
Subcellular Location	Mitochondrion matrix.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25ug/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 2-5ug/ml, Human, Mouse, Rat<br> Immunocytochemistry/Immunofluorescence, 5ug/ml, Human<br> Flow Cytometry (Fixed), 1-3ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5ug/ml, -<br>

Reference	1. Chaudhuri, M. M., Tonin, P. N., Lewis, W. H., Srinivasan, P. R. The gene for a novel protein, a member of the protein disulphide isomerase/Form I phosphoinositide-specific phospholipase C family, is amplified in hydroxyurea-resistant cells. Biochem. J. 281: 645-650, 1992.<br /><br />2. Hayano, T., Kikuchi, M. Cloning and sequencing of the cDNA encoding human P5. Gene 164: 377-378, 1995. <br /><br />3. Hoshijima, K., Metherall, J. E., Grunwald, D. J. A protein disulfide isomerase expressed in the embryonic midline is required for left/right asymmetries. Genes Dev. 16: 2518-2529, 2002. <br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003258-1	A03813-2	-	100 ug	$370		Add to Cart
BHA21003258-2	A03813-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003258-3	A03813-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003258-4	A03813-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003258-5	A03813-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003258-6	A03813-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003258-7	A03813-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003258-8	A03813-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003258-9	A03813-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003258-10	A03813-2-APC	APC	100 ug	$670		Add to Cart
BHA21003258-11	A03813-2-PE	PE	100 ug	$670		Add to Cart
BHA21003258-12	A03813-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003258-13	A03813-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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