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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PD-1/PDCD1 Antibody Picoband®

SKU : BHA21002708

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Mfr.No.	A00178, A00178-10ug, A00178-Biotin, A00178-Cy3, A00178-Dylight488, A00178-Dylight550, A00178-Dylight594, A00178-FITC, A00178-HRP, A00178-APC, A00178-PE, A00178-iFluor647, A00178-carrier-free
Alternative Names	SRY-box 9
Background	Transcription factor SOX-9 is a protein that in humans is encoded by the SOX9 gene. The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PD-1 PDCD1 Antibody catalog # A00178. Tested in Flow Cytometry, IF, IHC, WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcriptional regulator that plays a role in chondrocytes differentiation and skeletal development. Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219.
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the N-terminus of mouse PD1, different from the related human sequence by fifteen amino acids.
Isotype	Rabbit IgG
Molecular Weight	60 kDa
Reactivity	Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Specificity	No cross reactivity with other proteins.
Tissue Specificity	Expressed in all tissues, but more abundant in heart, brain and skeletal muscle.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Uniprot	Q02242
Gene Id	18566
Gene Name	PDCD1
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	IF, IHC, WB, Flow Cytometry
Description	Weste blot, 0.1-0.5 ug/ml, Mouse<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Mouse, Rat, By Heat<br> Immunofluorescence, 5 ug/ml, Mouse<br> Flow Cytometry(Fixed), 1-3 ug/1x10<sup>6</sup> cells, Mouse<br>

Reference	1. Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., Freeman, G. J., Ahmed, R. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687, 2006.<br /><br />2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010.<br /><br />3. Finger, L. R., Pu, J., Wasserman, R., Vibhakar, R., Louie, E., Hardy, R. R., Burrows, P. D., Billips, L. G. The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors. Gene 197: 177-187, 1997.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21002708-1	A00178	-	100 ug	$370		Add to Cart
BHA21002708-2	A00178-10ug	Sample	10 ug	$99		Add to Cart
BHA21002708-3	A00178-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21002708-4	A00178-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21002708-5	A00178-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21002708-6	A00178-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21002708-7	A00178-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21002708-8	A00178-FITC	FITC	100 ug	$570		Add to Cart
BHA21002708-9	A00178-HRP	HRP	100 ug	$570		Add to Cart
BHA21002708-10	A00178-APC	APC	100 ug	$670		Add to Cart
BHA21002708-11	A00178-PE	PE	100 ug	$670		Add to Cart
BHA21002708-12	A00178-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21002708-13	A00178-carrier-free	carrier-free	100 ug	$370		Add to Cart

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