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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PCMT1 Antibody Picoband®

SKU : BHA21005766

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Mfr.No.	A04579-2, A04579-2-10ug, A04579-2-Biotin, A04579-2-Cy3, A04579-2-Dylight488, A04579-2-Dylight550, A04579-2-Dylight594, A04579-2-FITC, A04579-2-HRP, A04579-2-APC, A04579-2-PE, A04579-2-iFluor647, A04579-2-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alteatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-PCMT1 Antibody Picoband® catalog # A04579-2. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human PCMT1 recombinant protein (Position: M1-K227). Human PCMT1 shares 96% and 95.6% amino acid (aa) sequence identity with mouse and rat PCMT1, respectively.
Isotype	IgG
Molecular Weight	25 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	P22061
Gene Id	5110
Gene Name	PCMT1
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.1-0.25 ug/ml, Human, Mouse, Rat<br> Immunohistochemistry, 2-5 ug/ml, Human, Rat<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. DeVry, C. G., Clarke, S. Assignment of the protein L-isoaspartate (D-aspartate) O-methyltransferase gene (PCMT1) to human chromosome bands 6q24-q25 with radiation hybrid mapping. Cytogenet. Cell Genet. 84: 130-131, 1999. <br /><br />2. Farrar, C., Clarke, S. Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-aspartyl) O-methyltransferase-deficient mice. J. Biol. Chem. 277: 27856-27863, 2002.<br /><br />3. Gross, M. B. Personal Communication. Baltimore, Md. 10/13/2022.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005766-1	A04579-2	-	100 ug	$370		Add to Cart
BHA21005766-2	A04579-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21005766-3	A04579-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005766-4	A04579-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005766-5	A04579-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005766-6	A04579-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005766-7	A04579-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005766-8	A04579-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21005766-9	A04579-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21005766-10	A04579-2-APC	APC	100 ug	$670		Add to Cart
BHA21005766-11	A04579-2-PE	PE	100 ug	$670		Add to Cart
BHA21005766-12	A04579-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005766-13	A04579-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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