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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PCDHA8 Antibody Picoband®

SKU : BHA21005760

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Mfr.No.	A15533, A15533-10ug, A15533-Biotin, A15533-Cy3, A15533-Dylight488, A15533-Dylight550, A15533-Dylight594, A15533-FITC, A15533-HRP, A15533-APC, A15533-PE, A15533-iFluor647, A15533-carrier-free
Alternative Names	Serine/threonine-protein kinase AtPK1/AtPK6
Background	This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alteative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.
Clonality	Polyclonal
Cross Reactivity	No cross reactivity with other proteins.
Description	Boster Bio Anti-PCDHA8 Antibody Picoband® catalog # A15533. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Downstream effector of TOR signaling pathway involved in osmotic stress response. Could be involved in the control of plant growth and development. Phosphorylates the ribosomal proteins P14, P16 and S6. Functions as a repressor of cell proliferation and r
Host	Rabbit
Immunogen Region	E.coli-derived human PCDHA8 recombinant protein (Position: H118-Q801).
Isotype	IgG
Molecular Weight	150 kDa
Reactivity	Human, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	70 kDa ribosomal protein S6 kinase 1 antibody, KS6B1_HUMAN antibody, p70 alpha antibody, P70 beta 1 antibody, p70 ribosomal S6 kinase alpha antibody, p70 ribosomal S6 kinase beta 1 antibody, p70 S6 kinase alpha antibody, P70 S6 Kinase antibody, p70 S6 kinase alpha 1 antibody, p70 S6 kinase alpha 2 antibody, p70 S6K antibody, p70 S6K-alpha antibody, p70 S6KA antibody, p70(S6K) alpha antibody, p70(S6K)-alpha antibody, p70-alpha antibody, p70-S6K 1 antibody, p70-S6K antibody, P70S6K antibody, P70S6K1 antibody, p70S6Kb antibody, PS6K antibody, Ribosomal protein S6 kinase 70kDa polypeptide 1 antibody, Ribosomal protein S6 kinase beta 1 antibody, Ribosomal protein S6 kinase beta-1 antibody, Ribosomal protein S6 kinase I antibody, RPS6KB1 antibody, S6K antibody, S6K-beta-1 antibody, S6K1 antibody, Serine/threonine kinase 14 alpha antibody, Serine/threonine-protein kinase 14A antibody, STK14A antibody
Tissue Specificity	Expressed in all tissues.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q9Y5H6
Gene Id	56140
Gene Name	PCDHA8
Subcellular Location	Cytoplasm. Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Rat<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Noonan, J. P., Li, J., Nguyen, L., Caoile, C., Dickson, M., Grimwood, J., Schmutz, J., Feldman, M. W., Myers, R. M. Extensive linkage disequilibrium, a common 16.7-kilobase deletion, and evidence of balancing selection in the human protocadherin alpha cluster. Am. J. Hum. Genet. 72: 621-635, 2003. <br /><br />2. Ribich, S., Tasic, B., Maniatis, T. Identification of long-range regulatory elements in the protocadherin-alpha gene cluster. Proc. Nat. Acad. Sci. 103: 19719-19724, 2006. <br /><br />3. Wu, Q., Maniatis, T. A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell 97: 779-790, 1999.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21005760-1	A15533	-	100 ug	$370		Add to Cart
BHA21005760-2	A15533-10ug	Sample	10 ug	$99		Add to Cart
BHA21005760-3	A15533-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21005760-4	A15533-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21005760-5	A15533-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21005760-6	A15533-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21005760-7	A15533-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21005760-8	A15533-FITC	FITC	100 ug	$570		Add to Cart
BHA21005760-9	A15533-HRP	HRP	100 ug	$570		Add to Cart
BHA21005760-10	A15533-APC	APC	100 ug	$670		Add to Cart
BHA21005760-11	A15533-PE	PE	100 ug	$670		Add to Cart
BHA21005760-12	A15533-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21005760-13	A15533-carrier-free	carrier-free	100 ug	$370		Add to Cart

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