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Home / Primary Antibodies / Polyclonal Antibodies

Anti-PAR-3/PARD3 Antibody Picoband®

SKU : BHA21003609

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Mfr.No.	A01897-2, A01897-2-10ug, A01897-2-Biotin, A01897-2-Cy3, A01897-2-Dylight488, A01897-2-Dylight550, A01897-2-Dylight594, A01897-2-FITC, A01897-2-HRP, A01897-2-APC, A01897-2-PE, A01897-2-iFluor647, A01897-2-carrier-free
Alternative Names	C-C chemokine receptor type 1
Background	Partitioning defective 3 homolog is a protein that in humans is encoded by the PARD3 gene. This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and polarized cell growth. Multiple alteatively spliced transcript variants have been described for this gene.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-PAR-3/PARD3 Antibody Picoband® catalog # A01897-2. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Receptor for a C-C type chemokine. Binds to MIP-1-alpha, RANTES, and less efficiently, to MIP-1-beta or MCP-1 and subsequently transduces a signal by increasing the intracellular calcium ions level. Responsible for affecting stem cell proliferation.
Host	Rabbit
Immunogen Region	E.coli-derived human PAR-3/PARD3 recombinant protein (Position: M1-Q1346).
Isotype	Rabbit IgG
Molecular Weight	151 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	C-C chemokine receptor type 1;C-C CKR-1;CC-CKR-1;CCR-1;CCR1;Macrophage inflammatory protein 1-alpha receptor;MIP-1alpha-R;RANTES-R;CD191;Ccr1;Cmkbr1;
Tissue Specificity	Detected in the heart, spleen, lung, peritoneal exudate cells and leukocytes.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q8TEW0
Gene Id	56288
Gene Name	PARD3
Subcellular Location	Cell membrane; Multi-pass membrane protein.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	WB, IHC, ICC, IF, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml, -

Reference	1. Chan, J. R., Jolicoeur, C., Yamauchi, J., Elliott, J., Fawcett, J. P., Ng, B. K., Cayouette, M. The polarity protein Par-3 ly interacts with p75(NTR) to regulate myelination. Science 314: 832-836, 2006. 2. Chen, X., An, Y., Gao, Y., Guo, L., Rui, L., Xie, H., Sun, M., Lam Hung, S., Sheng, X., Zou, J., Bao, Y., Guan, H., Niu, B., Li, Z., Finnell, R. H., Gusella, J. F., Wu, B.-L., Zhang, T. Rare deleterious PARD3 variants in the aPKC-binding region are implicated in the pathogenesis of human cranial neural tube defects via disrupting apical tight junction formation. Hum. Mutat. 38: 378-389, 2017. 3. Coureuil, M., Mikaty, G., Miller, F., Lecuyer, H., Beard, C., Bourdoulous, S., Dumenil, G., Mege, R.-M., Weksler, B. B., Romero, I. A., Couraud, P.-O., Nassif, X. Meningococcal type IV pili recruit the polarity complex to cross the brain endothelium. Science 325: 83-87, 2009.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003609-1	A01897-2	-	100 ug	$370		Add to Cart
BHA21003609-2	A01897-2-10ug	Sample	10 ug	$99		Add to Cart
BHA21003609-3	A01897-2-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003609-4	A01897-2-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003609-5	A01897-2-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003609-6	A01897-2-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003609-7	A01897-2-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003609-8	A01897-2-FITC	FITC	100 ug	$570		Add to Cart
BHA21003609-9	A01897-2-HRP	HRP	100 ug	$570		Add to Cart
BHA21003609-10	A01897-2-APC	APC	100 ug	$670		Add to Cart
BHA21003609-11	A01897-2-PE	PE	100 ug	$670		Add to Cart
BHA21003609-12	A01897-2-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003609-13	A01897-2-carrier-free	carrier-free	100 ug	$370		Add to Cart

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