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Home / Primary Antibodies / Polyclonal Antibodies

Anti-P2Y6 Receptor (extracellular)-FITC Antibody

SKU : BHA21301158

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Alomone Labs

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Mfr.No.	APR-106-F, APR-106-F_15 mcl, APR-106-F_50 mcl
Lead Time	1-2 Business Days
Immunogen Species	Mouse
Background	The nucleotide receptor P2Y6 binds UDP, and is a member of the G-protein coupled receptor superfamily1,3.P2Y6 agonists induce an inositol phosphate/Ca2+ response that is insensitive to pertussis toxin inhibition. P2Y6 is coupled to phospholipase C via Gq, and is also coupled to inhibition of N-type Ca2+ and M-type K+ channels1,2.P2Y6 mRNA is expressed in various rat tissues, including lung, stomach, intestine, spleen, heart, and aorta. P2Y6 was reported to mediate contractions in human cerebral arteries4.
Clonality	Polyclonal
Description	Anti-P2Y6 Receptor (extracellular) Antibody (#APR-106) is a highly specific antibody directed against an epitope of the mouse protein. The antibody can be used in western blot, immunohistochemistry, and indirect live cell flow cytometry applications. It has been designed to recognize P2RY6 from human, rat, and mouse samples. Anti-P2Y6 Receptor (extracellular)-FITC Antibody (#APR-106-F) is directly conjugated to fluorescein isothiocyanate (FITC). This labeled antibody can be used in immunofluorescent applications such as direct live cell flow cytometry.
Formulation	PBS pH7.4, 1% BSA with 0.05% sodium azide
Host	Rabbit
Immunogen Region	2nd extracellular loop
Isotype	Rabbit IgG
Reactivity	Human, Rat, Mouse
Reconstitution	15 ul or 50 ul double distilled water (DDW), depending on the sample size.
Shipping	Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C
Synonyms	P2Y purinoceptor 6, P2RY6
UNSPSC Code	41116161
Note	Homology: Mouse, rat - 14/15 amino acid residues identical; human - 12/15 amino acid residues identical Peptide confirmation: Confirmed by amino acid analysis and mass spectrometry Negative Control: RIC-001-F Specifictiy: P2RY6 Is Toxin: No Standard quality control of each lot: Western blot analysis (unlabeled antibody, #APR-106), and direct flow cytometry (labeled antibody). Antigen preadsorption control: 1 ug peptide per 1 ug antibody

Accession Number	Q9ERK9
Gene Id	233571
Target	P2Y purinoceptor 6, P2RY6
Sequence	(C)RNRTV(S)YDLSPPILS, corresponding to amino acid residues 172 - 186 of mouse P2RY6

Conjugates	Fluorescein isothiocyanate (FITC).

Concentration	1 mg/ml
Form	Lyophilized powder
Preservative	1% BSA, 0.05% NaN3
Purity	Affinity purified on immobilized antigen.
Storage	Storage After Reconstitution: The reconstituted solution can be stored at 4°C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min). Storage Before Reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C

Applications	FC, LCI
Dilution	Contact Alomone for information

Product Manual	SDS

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Combination SKU	Supplier No.	Size	Your price	Quantity
BHA21301158-1	APR-106-F_15 mcl	15 mcl	$597		Add to Cart
BHA21301158-2	APR-106-F_50 mcl	50 mcl	$797		Add to Cart
BHA21301158-3	APR-106-F_50 mcl	2x50 mcl	$1397		Add to Cart
BHA21301158-4	APR-106-F_50 mcl	5x50 mcl	$2743		Add to Cart
BHA21301158-5	APR-106-F_50 mcl	10x50 mcl	$3764		Add to Cart

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