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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Oct-1/POU2F1 Antibody Picoband®

SKU : BHA21000188

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Mfr.No.	PB9317, PB9317-10ug, PB9317-Biotin, PB9317-Cy3, PB9317-Dylight488, PB9317-Dylight550, PB9317-Dylight594, PB9317-FITC, PB9317-HRP, PB9317-APC, PB9317-PE, PB9317-iFluor647, PB9317-carrier-free
Alternative Names	POU domain, class 2, transcription factor 1
Background	POU domain, class 2, transcription factor 1, also known as OTF1 or OCT1, is a protein that in humans is encoded by the POU2F1 gene. The POU2F1 transcription factor was among the first identified members of the POU transcription factor family. This gene is mapped to 1q24.1 to q24.2. It has been found that the POU dimer from the POU2F1 gene formed on the palindromic OCT factor recognition element, or PORE (ATTTGAAATGCAAAT), could recruit the transcriptional coactivator OBF1 , whereas POU dimers formed on the consensus MORE (more PORE) (ATGCATATGCAT) or on MOREs from immunoglobulin heavy chain promoters (AT(G/A)(C/A)ATATGCAA) failed to interact. POU domain proteins contain a bipartite DNA-binding domain divided by a flexible linker that enables them to adopt various monomer configurations on DNA.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Oct-1/POU2F1 Antibody Picoband® catalog # PB9317. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3') and activates the promoters of the genes for some small nuclear RNAs (snRNA) and of genes such as those for histone H2B and immunoglobulins. Modulates transcription transactivation by N
Host	Rabbit
Immunogen Region	E.coli-derived human Oct-1 recombinant protein (Position: S11-Q240). Human Oct-1 shares 96% and 99% amino acid (aa) sequence identity with mouse and rat Oct-1, respectively.
Isotype	Rabbit IgG
Molecular Weight	90 kDa
Reactivity	Human
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	POU domain, class 2, transcription factor 1;NF-A1;Octamer-binding protein 1;Oct-1;Octamer-binding transcription factor 1;OTF-1;POU2F1;OCT1, OTF1;
Tissue Specificity	Ubiquitous. Isoform 2 is lymphocyte-specific.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Uniprot	P14859
Gene Id	5451
Gene Name	POU2F1
Sequence	Belongs to the POU transcription factor family. Class- 2 subfamily.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, By Heat Weste blot, 0.1-0.5ug/ml, Human

Reference	1. Hsieh, C.-L., Sturm, R., Herr, W., Francke, U. The gene for the ubiquitous octamer-binding protein Oct-1 is on human chromosome 1, region cen-q32, and near Ly-22 and Ltw-4 on mouse chromosome 1. Genomics 6: 666-672, 1990. 2. Tomilin, A., Remenyi, A., Lins, K., Bak, H., Leidel, S., Vriend, G., Wilmanns, M., Scholer, H. R.Synergism with the coactivator OBF-1 (OCA-B, BOB-1) is mediated by a specific POU dimer configuration. Cell 103: 853-864, 2000. 3. Roberts S, Segil N, Heintz N (October 1991). "Differential phosphorylation of the transcription factor Oct1 during the cell cycle". Science 253 (5023): 10226.

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Combination SKU	Supplier No.	Size	Conjugation	Your price	Quantity
BHA21000188-1	PB9317	100 ug	-	$370		Add to Cart
BHA21000188-2	PB9317-10ug	10 ug	Sample	$99		Add to Cart
BHA21000188-3	PB9317-Biotin	100 ug	Biotin	$570		Add to Cart
BHA21000188-4	PB9317-Cy3	100 ug	Cy3	$570		Add to Cart
BHA21000188-5	PB9317-Dylight488	100 ug	Dylight488	$570		Add to Cart
BHA21000188-6	PB9317-Dylight550	100 ug	Dylight550	$570		Add to Cart
BHA21000188-7	PB9317-Dylight594	100 ug	Dylight594	$570		Add to Cart
BHA21000188-8	PB9317-FITC	100 ug	FITC	$570		Add to Cart
BHA21000188-9	PB9317-HRP	100 ug	HRP	$570		Add to Cart
BHA21000188-10	PB9317-APC	100 ug	APC	$670		Add to Cart
BHA21000188-11	PB9317-PE	100 ug	PE	$670		Add to Cart
BHA21000188-12	PB9317-iFluor647	100 ug	iFluor647	$670		Add to Cart
BHA21000188-13	PB9317-carrier-free	100 ug	carrier-free	$370		Add to Cart

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