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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NXN/NRX Antibody Picoband®

SKU : BHA21003440

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Mfr.No.	A08028-1, A08028-1-10ug, A08028-1-Biotin, A08028-1-Cy3, A08028-1-Dylight488, A08028-1-Dylight550, A08028-1-Dylight594, A08028-1-FITC, A08028-1-HRP, A08028-1-APC, A08028-1-PE, A08028-1-iFluor647, A08028-1-carrier-free
Alternative Names	BMP and activin membrane bound inhibitor
Background	This gene encodes a member of the thioredoxin superfamily, a group of small, multifunctional redox-active proteins. Members of this family are characterized by a conserved active motif called the thioredoxin fold that catalyzes disulfide bond formation and isomerization. The encoded protein acts a redox-dependent regulator of the Wnt signaling pathway and is involved in cell growth and differentiation.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins.
Description	Boster Bio Anti-NXN/NRX Antibody Picoband® catalog # A08028-1. Tested in ELISA, Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Negatively regulates TGF-beta signaling.
Host	Rabbit
Immunogen Region	E.coli-derived human NXN/NRX recombinant protein (Position: E19-I435).
Isotype	Rabbit IgG
Molecular Weight	48 kDa
Reactivity	Human
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	BMP and activin membrane-bound inhibitor homolog; Non-metastatic gene A protein; Putative transmembrane protein; NMA; BAMBI; NMA
Tissue Specificity	Expressed in adult liver.
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q6DKJ4
Gene Id	64359
Gene Name	NXN
Subcellular Location	Cytoplasm . Nucleus . Translocates to nuclear foci during heat shock.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Applications	ELISA, Flow Cytometry, IF, IHC, ICC, WB
Description	Weste blot, 0.25-0.5 ug/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 ug/ml, Human<br> Immunocytochemistry/Immunofluorescence, 5 ug/ml, Human<br> Flow Cytometry (Fixed), 1-3 ug/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 ug/ml, -<br>

Reference	1. Hartz, P. A. Personal Communication. Baltimore, Md. 6/30/2009.<br /><br />2. Kurooka, H., Kato, K., Minoguchi, S., Takahashi, Y., Ikeda, J., Habu, S., Osawa, N., Buchberg, A. M., Moriwaki, K., Shisa, H., Honjo, T. Cloning and characterization of the nucleoredoxin gene that encodes a novel nuclear protein related to thioredoxin. Genomics 39: 331-339, 1997<br /><br />3. White, J. J., Mazzeu, J. F., Coban-Akdemir, Z., Bayram, Y., Bahrambeigi, V., Hoischen, A., van Bon, B. W. M., Gezdirici, A., Gulec, E. Y., Ramond, F., Touraine, R., Thevenon, J., and 24 others. WNT signaling perturbations underlie the genetic heterogeneity of Robinow syndrome. Am. J. Hum. Genet. 102: 27-43, 2018.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21003440-1	A08028-1	-	100 ug	$370		Add to Cart
BHA21003440-2	A08028-1-10ug	Sample	10 ug	$99		Add to Cart
BHA21003440-3	A08028-1-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21003440-4	A08028-1-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21003440-5	A08028-1-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21003440-6	A08028-1-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21003440-7	A08028-1-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21003440-8	A08028-1-FITC	FITC	100 ug	$570		Add to Cart
BHA21003440-9	A08028-1-HRP	HRP	100 ug	$570		Add to Cart
BHA21003440-10	A08028-1-APC	APC	100 ug	$670		Add to Cart
BHA21003440-11	A08028-1-PE	PE	100 ug	$670		Add to Cart
BHA21003440-12	A08028-1-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21003440-13	A08028-1-carrier-free	carrier-free	100 ug	$370		Add to Cart

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