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Home / Primary Antibodies / Polyclonal Antibodies

Anti-Nuclear respiratory factor 1 NRF1 Antibody Picoband®

SKU : BHA21007186

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Mfr.No.	PA1948, PA1948-10ug, PA1948-Biotin, PA1948-Cy3, PA1948-Dylight488, PA1948-Dylight550, PA1948-Dylight594, PA1948-FITC, PA1948-HRP, PA1948-APC, PA1948-PE, PA1948-iFluor647, PA1948-carrier-free
Alternative Names	Nuclear respiratory factor 1
Background	Nuclear respiratory factor 1, is also known as NRF1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alteative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for "nuclear factor (erythroid-derived 2)-like 1" which has an official symbol of NFE2L1.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-Nuclear respiratory factor 1 NRF1 Antibody catalog # PA1948. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Transcription factor that activates the expression of the EIF2S1 (EIF2-alpha) gene. Links the transcriptional modulation of key metabolic genes to cellular growth and development. Implicated in the control of nuclear genes required for respiration, heme b
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence in the middle region of human NRF1, identical to the related rat and mouse sequences.
Isotype	Rabbit IgG
Molecular Weight	75 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Nuclear respiratory factor 1;NRF-1;Alpha palindromic-binding protein;Alpha-pal;NRF1;
Tissue Specificity	Ubiquitously expressed with strongest expression in skeletal muscle.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	Q16656
Gene Name	NRF1
Sequence	Belongs to the NRF1/Ewg family.
Subcellular Location	Nucleus.

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, ICC, WB
Description	Immunocytochemistry , 0.5-1ug/ml, Human, Mouse, Rat<br>Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Human, Rat, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Human, Rat, Mouse<br>

Reference	1. Efiok, B. J. S., Chiorini, J. A., Safer, B. A key transcription factor for eukaryotic initiation factor-2-alpha is strongly homologous to developmental transcription factors and may link metabolic genes to cellular growth and development. J. Biol. Chem. 269: 18921-18930, 1994.<br /><br />2. Gopalakrishnan, L., Scarpulla, R. C. Structure, expression, and chromosomal assignment of the human gene encoding nuclear respiratory factor 1. J. Biol. Chem. 270: 18019-18025, 1995.<br /><br />3. Virbasius, J. V., Scarpulla, R. C. Activation of the human mitochondrial transcription factor A gene by nuclear respiratory factors: a potential regulatory link between nuclear and mitochondrial gene expression in organelle biogenesis. Proc. Nat. Acad. Sci. 91: 1309-1313, 1994.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21007186-1	PA1948	-	100 ug	$370		Add to Cart
BHA21007186-2	PA1948-10ug	Sample	10 ug	$99		Add to Cart
BHA21007186-3	PA1948-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21007186-4	PA1948-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21007186-5	PA1948-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21007186-6	PA1948-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21007186-7	PA1948-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21007186-8	PA1948-FITC	FITC	100 ug	$570		Add to Cart
BHA21007186-9	PA1948-HRP	HRP	100 ug	$570		Add to Cart
BHA21007186-10	PA1948-APC	APC	100 ug	$670		Add to Cart
BHA21007186-11	PA1948-PE	PE	100 ug	$670		Add to Cart
BHA21007186-12	PA1948-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21007186-13	PA1948-carrier-free	carrier-free	100 ug	$370		Add to Cart

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