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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NSMAF Antibody Picoband®

SKU : BHA21006454

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Mfr.No.	A09560, A09560-10ug, A09560-Biotin, A09560-Cy3, A09560-Dylight488, A09560-Dylight550, A09560-Dylight594, A09560-FITC, A09560-HRP, A09560-APC, A09560-PE, A09560-iFluor647, A09560-carrier-free
Alternative Names	neutral sphingomyelinase activation associated factor
Background	This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alteative splicing results in multiple transcript variants.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-NSMAF Antibody Picoband® catalog # A09560. Tested in WB, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Host	Rabbit
Immunogen Region	E.coli-derived human NSMAF recombinant protein (Position: K51-L868). Human NSMAF shares 92.3% amino acid (aa) sequence identity with mouse NSMAF.
Isotype	Rabbit IgG
Molecular Weight	104 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Synonyms	NSMAF; FAN; Protein FAN; Factor associated with neutral sphingomyelinase activation; Factor associated with N-SMase activation
Note	Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Uniprot	Q92636
Gene Id	8439
Gene Name	NSMAF

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months.Avoid repeated freezing and thawing.

Applications	WB, Flow Cytometry, ELISA
Description	Weste blot, 0.25-0.5 ug/ml, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 ug/1x10⁶ cells, Human ELISA, 0.1-0.5 ug/ml

Reference	1. Adam-Klages, S., Adam, D., Wiegmann, K., Struve, S., Kolanus, W., Schneider-Mergener, J., Kronke, M. FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase. Cell 86: 937-947, 1996. 2. Montfort, A., de Badts, B., Douin-Echinard, V., Martin, P. G. P., Iacovoni, J., Nevoit, C., Therville, N., Garcia, V., Bertrand, M.-A., Bessieres, M.-H., Trombe, M.-C., Levade, T., Benoist, H., Segui, B. FAN stimulates TNF-alpha-induced gene expression, leukocyte recruitment, and humoral response. J. Immun. 183: 5369-5378, 2009. 3. Segui, B., Cuvillier, O., Adam-Klages, S., Garcia, V., Malagarie-Cazenave, S., Leveque, S., Caspar-Bauguil, S., Coudert, J., Salvayre, R., Kronke, M., Levade, T. Involvement of FAN in TNF-induced apoptosis. J. Clin. Invest. 108: 143-151, 2001.

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006454-1	A09560	-	100 ug	$370		Add to Cart
BHA21006454-2	A09560-10ug	Sample	10 ug	$99		Add to Cart
BHA21006454-3	A09560-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006454-4	A09560-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006454-5	A09560-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006454-6	A09560-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006454-7	A09560-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006454-8	A09560-FITC	FITC	100 ug	$570		Add to Cart
BHA21006454-9	A09560-HRP	HRP	100 ug	$570		Add to Cart
BHA21006454-10	A09560-APC	APC	100 ug	$670		Add to Cart
BHA21006454-11	A09560-PE	PE	100 ug	$670		Add to Cart
BHA21006454-12	A09560-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006454-13	A09560-carrier-free	carrier-free	100 ug	$370		Add to Cart

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