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Home / Primary Antibodies / Polyclonal Antibodies

Anti-NSE/ENO2 Antibody Picoband®

SKU : BHA21006645

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Mfr.No.	PA1061, PA1061-10ug, PA1061-Biotin, PA1061-Cy3, PA1061-Dylight488, PA1061-Dylight550, PA1061-Dylight594, PA1061-FITC, PA1061-HRP, PA1061-APC, PA1061-PE, PA1061-iFluor647, PA1061-carrier-free
Alternative Names	Gamma-enolase
Background	NSE (neuron specific enolase), also known as Enolase 2 (ENO2), is found in elevated concentrations in plasma in certain neoplasias. The enolases catalyze the interconversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. ENO2 gene contains 12 exons distributed over 9,213 nucleotides. Human neurone-specific enolase is mapped to chromosome 12p13.
Clonality	Polyclonal
Cross Reactivity	No cross-reactivity with other proteins
Description	Boster Bio Anti-NSE/ENO2 Antibody catalog # PA1061. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Weste blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
Function	Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity). .
Host	Rabbit
Immunogen Region	A synthetic peptide corresponding to a sequence at the C-terminus of human NSE, identical to the related mouse and rat sequences.
Isotype	Rabbit IgG
Molecular Weight	47 kDa
Reactivity	Human, Mouse, Rat
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Specificity	No cross reactivity with other proteins.
Synonyms	Gamma-enolase;4.2.1.11;2-phospho-D-glycerate hydro-lyase;Enolase 2;Neural enolase;Neuron-specific enolase;NSE;ENO2;
Tissue Specificity	The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Note	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Uniprot	P09104
Gene Name	ENO2
Sequence	Belongs to the enolase family.
Subcellular Location	Cytoplasm . Cell membrane . Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form. .

Conjugates	Biotin, Cy3, Dylight488, Dylight550, Dylight594, FITC, HRP, APC, PE, iFluor647, carrier-free

Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml.
Form	Lyophilized
Purification	Immunogen affinity purified.
Storage	Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Applications	IHC, WB
Description	Immunohistochemistry (Paraffin-embedded Section), 0.5-1ug/ml, Rat, Human, Mouse, By Heat<br>Weste blot, 0.1-0.5ug/ml, Rat, Human, Mouse<br>

Reference	1. Craig, S. P.; Day, I. N. M.; Thompson, R. J.; Craig, I. W. : Localization of human neurone-specific enolase to chromosome 12p13. (Abstract) Cytogenet. Cell Genet. 51: 980 only, 1989. <br /><br />2. Craig, S. P.; Day, I. N. M.; Thompson, R. J.; Craig, I. W. : Localisation of neurone-specific enolase (ENO2) to 12p13. Cytogenet. Cell Genet. 54: 71-73, 1990. <br /><br />3. Mattei, J. F.; Baeteman, M. A.; Mattei, M. G.; Ardissonne, J. P.; Giraud, F. : Regional assignments of CS and ENO2 on chromosome 12. (Abstract) Cytogenet. Cell Genet. 32: 297 only, 1982.<br /><br />

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Combination SKU	Supplier No.	Conjugation	Size	Your price	Quantity
BHA21006645-1	PA1061	-	100 ug	$370		Add to Cart
BHA21006645-2	PA1061-10ug	Sample	10 ug	$99		Add to Cart
BHA21006645-3	PA1061-Biotin	Biotin	100 ug	$570		Add to Cart
BHA21006645-4	PA1061-Cy3	Cy3	100 ug	$570		Add to Cart
BHA21006645-5	PA1061-Dylight488	Dylight488	100 ug	$570		Add to Cart
BHA21006645-6	PA1061-Dylight550	Dylight550	100 ug	$570		Add to Cart
BHA21006645-7	PA1061-Dylight594	Dylight594	100 ug	$570		Add to Cart
BHA21006645-8	PA1061-FITC	FITC	100 ug	$570		Add to Cart
BHA21006645-9	PA1061-HRP	HRP	100 ug	$570		Add to Cart
BHA21006645-10	PA1061-APC	APC	100 ug	$670		Add to Cart
BHA21006645-11	PA1061-PE	PE	100 ug	$670		Add to Cart
BHA21006645-12	PA1061-iFluor647	iFluor647	100 ug	$670		Add to Cart
BHA21006645-13	PA1061-carrier-free	carrier-free	100 ug	$370		Add to Cart

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